Oncological adequacy of R1 vascular margin in minimally invasive liver surgery for hepatocellular carcinoma and colorectal liver metastases: a meta-analysis

The concept of tumor-vessel detachment (R1 vascular [R1v]), has recently gained attention within the minimally invasive (MI) setting, but its oncological adequacy remains poorly defined. This meta-analysis aims to assess the outcomes of MI-R1v hepatectomy for hepatocellular carcinoma (HCC) and color...

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Main Authors:	Procopio, Fabio (Author) , Memeo, Riccardo (Author) , Del Fabbro, Daniele (Author) , Abdelhadi, Schaima (Author) , Reißfelder, Christoph (Author) , Edwin, Bjørn (Author) , Milana, Flavio (Author) , Troisi, Roberto Ivan (Author) , Torzilli, Guido (Author) , Caringi, Silvio (Author) , Valle, Raffaele Dalla (Author) , Giuffrida, Mario (Author) , Drejian, Sarkis (Author) , Montalti, Roberto (Author) , Rompianesi, Gianluca (Author) , Muttillo, Edoardo M. (Author) , Chiarella, Leonardo L. (Author) , Ratti, Francesca (Author) , Magistri, Paolo (Author) , Belli, Andrea (Author) , Berardi, Giammauro (Author) , Ettorre, Giuseppe M. (Author) , Ceccarelli, Graziano (Author) , Izzo, Francesco (Author) , Spampinato, Marcello Giuseppe (Author) , Angelis, Nicola De’ (Author) , Pessaux, Patrick (Author) , Piardi, Tullio (Author) , Di Benedetto, Fabrizio (Author)
Format:	Article (Journal)
Language:	English
Published:	08 January 2026
In:	Annals of surgical oncology
ISSN:	1534-4681
DOI:	10.1245/s10434-025-18922-1
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1245/s10434-025-18922-1
Author Notes:	Fabio Procopio, MD, Riccardo Memeo, MD, PhD, Daniele Del Fabbro, MD, Schaima Abdelhadi, MD, PhD, Christoph Reissfelder, MD, PhD, MHBA, Bjørn Edwin, MD, PhD, Flavio Milana, MD, Roberto Ivan Troisi, MSc, MD, PhD, FEBS, and Guido Torzilli, MD, PhD, FACS, Minimally Invasive R1 Vascular Group