Optimizing whole-body MRI for early cancer detection in Li-Fraumeni syndrome: a prospective bicentric study
Annual whole-body MRI (WB-MRI) is recommended for early cancer detection in individuals with Li-Fraumeni syndrome (LFS). However, there is no agreement on a standardized MRI protocol. This study evaluated the diagnostic performance of different MRI sequences to suggest an optimized protocol for LFS...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
21 October 2025
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| In: |
European radiology
Year: 2025, Pages: 1-12 |
| ISSN: | 1432-1084 |
| DOI: | 10.1007/s00330-025-11880-y |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00330-025-11880-y Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00330-025-11880-y?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=clarivate |
| Verfasserangaben: | Myriam Margareta Keymling, Felix Tobias Kurz, Tristan Anselm Kuder, Sebastian Bickelhaupt, Thomas Hielscher, Robert Hog, Theresa Mokry, Tawfik Moher Alsady, Sarah Schott, Christian Kratz, Diane Miriam Renz and Heinz-Peter Schlemmer |
| Zusammenfassung: | Annual whole-body MRI (WB-MRI) is recommended for early cancer detection in individuals with Li-Fraumeni syndrome (LFS). However, there is no agreement on a standardized MRI protocol. This study evaluated the diagnostic performance of different MRI sequences to suggest an optimized protocol for LFS surveillance. |
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| Beschreibung: | Gesehen am 13.02.2026 |
| Beschreibung: | Online Resource |
| ISSN: | 1432-1084 |
| DOI: | 10.1007/s00330-025-11880-y |