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ECG-based identification of COPD patients at risk for atrial fibrillation and its impact on adverse clinical outcomes—a subgroup analysis of the prospective multicenter COSYCONET cohort

Atrial fibrillation (AF) frequently occurs in patients with chronic obstructive pulmonary disease (COPD) and is associated with adverse clinical outcomes. We aimed to identify patients at risk for AF using amplified p-wave duration (APWD) analysis on electrocardiogram (ECG) as non-invasive tool to d...

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Main Authors: Eichenlaub, Martin (Author) , Frye, Björn Christian (Author) , Lehrmann, Heiko (Author) , Biertz, Frank (Author) , Jadidi, Amir Sherwan (Author) , Kaier, Klaus (Author) , Melzer, Thomas (Author) , Alter, Peter (Author) , Watz, Henrik (Author) , Waschki, Benjamin (Author) , Weckler, Barbara Christine (Author) , Trudzinski, Franziska (Author) , Michels-Zetsche, Julia D. (Author) , Trinkmann, Frederik (Author) , Herth, Felix (Author) , Kauczor, Hans-Ulrich (Author) , Kahnert, Kathrin (Author) , Jörres, Rudolf (Author) , Bals, Robert (Author) , Westermann, Dirk (Author) , Arentz, Thomas (Author) , Vogelmeier, Claus Franz (Author) , Stolz, Daiana (Author) , Fähndrich, Sebastian (Author)
Format: Article (Journal)
Language:English
Published: 17 September 2025
In: Respiratory research
Year: 2025, Volume: 26, Issue: 1, Pages: 1-15
ISSN:1465-993X
DOI:10.1186/s12931-025-03342-2
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12931-025-03342-2
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1186/s12931-025-03342-2
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Author Notes:Martin Eichenlaub, Björn Christian Frye, Heiko Lehrmann, Frank Biertz, Amir Sherwan Jadidi, Klaus Kaier, Thomas Melzer, Peter Alter, Henrik Watz, Benjamin Waschki, Barbara Christine Weckler, Franziska Christina Trudzinski, Julia Dorothea Michels-Zetsche, Frederik Trinkmann, Felix Josef-Friedrich Herth, Hans-Ulrich Kauczor, Kathrin Kahnert, Rudolf Jörres, Robert Bals, Dirk Westermann, Thomas Arentz, Claus Franz Vogelmeier, Daiana Stolz, Sebastian Fähndrich, and on behalf of the German COSYCONET cohort
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Summary:Atrial fibrillation (AF) frequently occurs in patients with chronic obstructive pulmonary disease (COPD) and is associated with adverse clinical outcomes. We aimed to identify patients at risk for AF using amplified p-wave duration (APWD) analysis on electrocardiogram (ECG) as non-invasive tool to diagnose an atrial cardiomyopathy (AtCM) which is an established risk factor for AF.
Item Description:Gesehen am 18.02.2026
Physical Description:Online Resource
ISSN:1465-993X
DOI:10.1186/s12931-025-03342-2

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