Neuropsychiatric events following high-dose steroid administration during early immune checkpoint therapy are more frequent with extended steroid exposure

Patients on immune checkpoint therapy (ICT) are at risk for neuropsychiatric events due to the use of steroids in managing immune-related adverse effects. We aimed to characterize neuropsychiatric events after the initial administration of high-dose steroids following early ICT.

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Bibliographic Details
Main Authors: Lacourt, Tamara E. (Author) , Schubert, Marc Cicero (Author) , Siddiqui, Bilal A. (Author) , Subudhi, Sumit K. (Author) , Chopra, Deepti A. (Author)
Format: Article (Journal)
Language:English
Published: 08 November 2025
In: Supportive care in cancer
Year: 2025, Volume: 33, Issue: 12, Pages: 1-9
ISSN:1433-7339
DOI:10.1007/s00520-025-10083-x
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00520-025-10083-x
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s00520-025-10083-x?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=clarivate
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Author Notes:Tamara E. Lacourt, Marc C. Schubert, Bilal A. Siddiqui, Sumit K. Subudhi, Deepti A. Chopra
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Summary:Patients on immune checkpoint therapy (ICT) are at risk for neuropsychiatric events due to the use of steroids in managing immune-related adverse effects. We aimed to characterize neuropsychiatric events after the initial administration of high-dose steroids following early ICT.
Item Description:Gesehen am 20.02.2026
Physical Description:Online Resource
ISSN:1433-7339
DOI:10.1007/s00520-025-10083-x