Neuropsychiatric events following high-dose steroid administration during early immune checkpoint therapy are more frequent with extended steroid exposure
Patients on immune checkpoint therapy (ICT) are at risk for neuropsychiatric events due to the use of steroids in managing immune-related adverse effects. We aimed to characterize neuropsychiatric events after the initial administration of high-dose steroids following early ICT.
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
08 November 2025
|
| In: |
Supportive care in cancer
Year: 2025, Volume: 33, Issue: 12, Pages: 1-9 |
| ISSN: | 1433-7339 |
| DOI: | 10.1007/s00520-025-10083-x |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00520-025-10083-x Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s00520-025-10083-x?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=clarivate |
| Author Notes: | Tamara E. Lacourt, Marc C. Schubert, Bilal A. Siddiqui, Sumit K. Subudhi, Deepti A. Chopra |
MARC
| LEADER | 00000naa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1962045366 | ||
| 003 | DE-627 | ||
| 005 | 20260220134005.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 260220s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00520-025-10083-x |2 doi | |
| 035 | |a (DE-627)1962045366 | ||
| 035 | |a (DE-599)KXP1962045366 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Lacourt, Tamara E. |e VerfasserIn |0 (DE-588)1390845621 |0 (DE-627)196204565X |4 aut | |
| 245 | 1 | 0 | |a Neuropsychiatric events following high-dose steroid administration during early immune checkpoint therapy are more frequent with extended steroid exposure |c Tamara E. Lacourt, Marc C. Schubert, Bilal A. Siddiqui, Sumit K. Subudhi, Deepti A. Chopra |
| 264 | 1 | |c 08 November 2025 | |
| 300 | |b Diagramme | ||
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 20.02.2026 | ||
| 520 | |a Patients on immune checkpoint therapy (ICT) are at risk for neuropsychiatric events due to the use of steroids in managing immune-related adverse effects. We aimed to characterize neuropsychiatric events after the initial administration of high-dose steroids following early ICT. | ||
| 650 | 4 | |a Adverse events | |
| 650 | 4 | |a Cancer | |
| 650 | 4 | |a Corticosteroids | |
| 650 | 4 | |a Immunotherapy | |
| 650 | 4 | |a Neuropsychiatric | |
| 650 | 4 | |a Steroids | |
| 700 | 1 | |a Schubert, Marc Cicero |e VerfasserIn |0 (DE-588)1264158912 |0 (DE-627)1812829779 |4 aut | |
| 700 | 1 | |a Siddiqui, Bilal A. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Subudhi, Sumit K. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Chopra, Deepti A. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Supportive care in cancer |d Berlin : Springer, 1993 |g 33(2025), 12, Artikel-ID 1031, Seite 1-9 |h Online-Ressource |w (DE-627)254909574 |w (DE-600)1463166-0 |w (DE-576)074754076 |x 1433-7339 |7 nnas |a Neuropsychiatric events following high-dose steroid administration during early immune checkpoint therapy are more frequent with extended steroid exposure |
| 773 | 1 | 8 | |g volume:33 |g year:2025 |g number:12 |g elocationid:1031 |g pages:1-9 |g extent:9 |a Neuropsychiatric events following high-dose steroid administration during early immune checkpoint therapy are more frequent with extended steroid exposure |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00520-025-10083-x |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |7 1 |
| 856 | 4 | 0 | |u https://link.springer.com/article/10.1007/s00520-025-10083-x?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=clarivate |x Verlag |z lizenzpflichtig |3 Volltext |7 1 |
| 951 | |a AR | ||
| 992 | |a 20260220 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 1264158912 |a Schubert, Marc Cicero |m 1264158912:Schubert, Marc Cicero |d 50000 |e 50000PS1264158912 |k 0/50000/ |p 2 | ||
| 999 | |a KXP-PPN1962045366 |e 4920568738 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"name":{"displayForm":["Tamara E. Lacourt, Marc C. Schubert, Bilal A. Siddiqui, Sumit K. Subudhi, Deepti A. Chopra"]},"origin":[{"dateIssuedKey":"2025","dateIssuedDisp":"08 November 2025"}],"note":["Gesehen am 20.02.2026"],"person":[{"family":"Lacourt","given":"Tamara E.","role":"aut","display":"Lacourt, Tamara E."},{"given":"Marc Cicero","family":"Schubert","display":"Schubert, Marc Cicero","role":"aut"},{"role":"aut","display":"Siddiqui, Bilal A.","given":"Bilal A.","family":"Siddiqui"},{"display":"Subudhi, Sumit K.","role":"aut","given":"Sumit K.","family":"Subudhi"},{"family":"Chopra","given":"Deepti A.","role":"aut","display":"Chopra, Deepti A."}],"relHost":[{"recId":"254909574","disp":"Neuropsychiatric events following high-dose steroid administration during early immune checkpoint therapy are more frequent with extended steroid exposureSupportive care in cancer","pubHistory":["1.1993 -"],"type":{"media":"Online-Ressource","bibl":"periodical"},"id":{"eki":["254909574"],"zdb":["1463166-0"],"issn":["1433-7339"]},"language":["eng"],"title":[{"subtitle":"official journal of the Multinational Association of Supportive Care in Cancer","title_sort":"Supportive care in cancer","title":"Supportive care in cancer"}],"physDesc":[{"extent":"Online-Ressource"}],"part":{"pages":"1-9","volume":"33","extent":"9","year":"2025","text":"33(2025), 12, Artikel-ID 1031, Seite 1-9","issue":"12"},"origin":[{"dateIssuedKey":"1993","publisherPlace":"Berlin ; Heidelberg ; New York,NY","dateIssuedDisp":"1993-","publisher":"Springer"}],"note":["Gesehen am 06.12.05"]}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"recId":"1962045366","physDesc":[{"extent":"9 S.","noteIll":"Diagramme"}],"id":{"eki":["1962045366"],"doi":["10.1007/s00520-025-10083-x"]},"language":["eng"],"title":[{"title":"Neuropsychiatric events following high-dose steroid administration during early immune checkpoint therapy are more frequent with extended steroid exposure","title_sort":"Neuropsychiatric events following high-dose steroid administration during early immune checkpoint therapy are more frequent with extended steroid exposure"}]} | ||
| SRT | |a LACOURTTAMNEUROPSYCH0820 | ||