Long-term effects of empagliflozin in patients with chronic kidney disease
Two years of empagliflozin slowed kidney disease progression and reduced cardiovascular risk. In this post-trial study, empagliflozin had additional cardiorenal benefits after discontinuation.
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
February 20, 2025
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| In: |
The New England journal of medicine
Year: 2025, Volume: 392, Issue: 8, Pages: 777-787 |
| ISSN: | 1533-4406 |
| DOI: | 10.1056/NEJMoa2409183 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1056/NEJMoa2409183 Verlag, lizenzpflichtig, Volltext: https://www.nejm.org/doi/full/10.1056/NEJMoa2409183 
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| Author Notes: | the EMPA‑KIDNEY Collaborative Group |
| Summary: | Two years of empagliflozin slowed kidney disease progression and reduced cardiovascular risk. In this post-trial study, empagliflozin had additional cardiorenal benefits after discontinuation. |
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| Item Description: | Online veröffentlicht: 25. Oktober 2024 Mitglieder des "writing committee": William G. Herrington, F.R.C.P., Natalie Staplin, Ph.D., Nikita Agrawal, M.B., B.Chir., Christoph Wanner, M.D., Jennifer B. Green, M.D., Sibylle J. Hauske, Ph.D., Jonathan R. Emberson, Ph.D., David Preiss, Ph.D., Parminder Judge, Ph.D., Doreen Zhu, M.D., Rejive Dayanandan, M.Sc., Ryoki Arimoto, M.B., B.S., Kaitlin J. Mayne, M.B., Ch.B., Sarah Y.A. Ng, Ph.D., Emily Sammons, M.B., Ch.B., Michael Hill, D.Phil., Will Stevens, Ph.D., Karl Wallendszus, M.Sc., Susanne Brenner, M.D., Alfred K. Cheung, M.D., Zhi‑Hong Liu, M.D., Ph.D., Jing Li, Ph.D., Lai Seong Hooi, F.R.C.P., Wen Liu, F.R.C.P., Takashi Kadowaki, M.D., Ph.D., Masaomi Nangaku, M.D., Ph.D., Adeer Levin, M.D., David Z.I Cherney, M.D., Ph.D., Aldo P. Maggioni, M.D., Roberto Pontremoli, M.D., Rajat Deo, M.D., Shinya Goto, M.D., Ph.D., Xavier Rossello, Ph.D., Katherine R. Tuttle, M.D., Dominik Steubl, M.D., Dan Massey, M.Sc., Martina Brueckmann, M.D., Martin J. Landray, F.Med.Sci., Colin Baigent, F.Med.Sci., and Richard Haynes, D.M Gesehen am 23.02.2026 |
| Physical Description: | Online Resource |
| ISSN: | 1533-4406 |
| DOI: | 10.1056/NEJMoa2409183 |