Outcome in patients with secundum type atrial septal defect referred for percutaneous or surgical closure: a single-center experience : pediatric and congenital cardiology
This single-center, retrospective analysis presents data from 611 patients with a secundum type atrial septal defect (ASD II) closure. Included were patients >2 years of age. Patients presented at a median (range) age of 6.95 (2-86) years for interventional closure of ASD II. Out of 611 patients,...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
Januar 2026
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| In: |
The thoracic and cardiovascular surgeon
Year: 2026, Volume: 74, Issue: S 3, Pages: 1-8 |
| ISSN: | 1439-1902 |
| DOI: | 10.1055/a-2786-1128 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1055/a-2786-1128 Verlag, kostenfrei, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/a-2786-1128 
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| Author Notes: | Johanna Gorenflo, Victoria Ziesenitz, Mina Farag, Tsvetomir Loukanov, Matthias Gorenflo |
| Summary: | This single-center, retrospective analysis presents data from 611 patients with a secundum type atrial septal defect (ASD II) closure. Included were patients >2 years of age. Patients presented at a median (range) age of 6.95 (2-86) years for interventional closure of ASD II. Out of 611 patients, 215 underwent intracardiac repair based on transthoracic echocardiography (ECHO) findings. Transcatheter device closure was attempted and successfully performed in 300 out of 396 patients (Amplatzer™ Septal Occluder [ASO], n = 290 patients). Follow-up was 3.3 years (1 day-21.8 years) in patients with interventional closure of ASD II and 0.7 years (3 days-14.7 years; p < 0.001; Mann-Whitney) in patients after surgical closure. There was no in-hospital mortality in both groups. One patient, after Amplatzer device closure with an absent aortic rim, developed erosion, which was treated by cardiac surgery and patch closure of ASD II. Two patients showed dislocation of the device. In 231 out of 396 patients, right ventricular dimension normalized completely as determined on the last follow-up visit. Six patients at a median age of 60 (49.4-68.7) years presented with atrial fibrillation, which persisted after ASD II closure. About 26 patients (6.6%) showed pulmonary hypertension (PH), with 1 presenting with coincidental ASD II and severe PH. Closure of ASD II can be accomplished safely by interventional catheterization and intracardiac repair. In most cases, perioperative transthoracic and transesophageal ECHO is sufficient to decide whether a surgical approach or interventional closure is the best option to close the defect. |
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| Item Description: | Artikel online veröffentlicht: 02. Februar 2026 Gesehen am 09.03.2026 |
| Physical Description: | Online Resource |
| ISSN: | 1439-1902 |
| DOI: | 10.1055/a-2786-1128 |