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Abdominal T1 relaxation times at 7T

Objective: To quantify the T1 relaxation times at 7T for key abdominal organs and tissues, including the liver, kidney, spleen, and skeletal paraspinal muscles. Materials and methods: T1 mapping was performed on a 7T whole-body scanner with a parallel transmission (pTx) system in five healthy volunt...

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Main Authors: Bulanov, Petr (Author) , Menshchikov, Petr (Author) , Grimm, Johannes (Author) , Himburg, Niklas (Author) , Schmidt, Simon (Author) , Orzada, Stephan (Author) , Ladd, Mark E. (Author) , Schmitter, Sebastian (Author)
Format: Article (Journal)
Language:English
Published: 03 January 2026
In: Magnetic resonance materials in physics, biology and medicine
Year: 2026, Pages: 1-13
ISSN:1352-8661
DOI:10.1007/s10334-025-01317-4
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s10334-025-01317-4
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Author Notes:Petr Bulanov, Petr Menshchikov, Johannes A. Grimm, Niklas Himburg, Simon Schmidt, Stephan Orzada, Mark E. Ladd, Sebastian Schmitter
Description
Summary:Objective: To quantify the T1 relaxation times at 7T for key abdominal organs and tissues, including the liver, kidney, spleen, and skeletal paraspinal muscles. Materials and methods: T1 mapping was performed on a 7T whole-body scanner with a parallel transmission (pTx) system in five healthy volunteers. Static pTx (B1+ shimming) was applied to maximize B1+ magnitude in the target region. For each T1 map, data were collected using eight snapshot gradient-echo inversion recovery sequences during breath holding. Voxel-wise T1 values were calculated based on DICOM data using exponential model fitting. Results: Mean abdomen T1 values and corresponding coefficients of variation across the group were: 1829 ± 60 ms, 3.3% for the kidney cortex; 2619 ± 83 ms, 3.2% for the kidney medulla; 1378 ± 48 ms, 3.5% for the liver; 1954 ± 28 ms, 1.4% for the skeletal paraspinal muscle; 1770 ± 36 ms, 2.0% for the spleen. Conclusion: In this study, we quantified the T1 relaxation times at 7T for key abdominal organs and tissues, including the liver, kidney, spleen, and skeletal paraspinal muscle. To achieve this, pTx was applied to mitigate B1+ dropouts in the target regions. The B1+ insensitive snapshot gradient-echo inversion recovery method was utilized to acquire accurate and reproducible T1 maps.
Item Description:Online veröffentlicht: 03. Januar 2026
Gesehen am 11.03.2026
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Physical Description:Online Resource
ISSN:1352-8661
DOI:10.1007/s10334-025-01317-4

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