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Effectiveness, barriers, and facilitating factors of strategies for active delabeling of patients with penicillin allergy labels: a systematic review

Penicillin allergy is the most frequently reported allergy in hospitalized patients, although rarely confirmed. Given the negative outcomes associated with incorrect penicillin allergy diagnoses, implementation of programmatic delabeling strategies is important for successful antibiotic stewardship....

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Main Authors: Nürnberg, Hannah (Author) , Denkinger, Claudia M. (Author) , Krause, Tabea (Author) , Oetken, Lars (Author) , Rauer, Sophie (Author) , Rapp, Amelie (Author) , Kern, Lisa Marie (Author) , Hoppe-Tichy, Torsten (Author) , Schöning, Tilman (Author) , Khatamzas, Elham (Author) , Morath, Benedict (Author)
Format: Article (Journal)
Language:English
Published: 20 november 2025
In: Infection
Year: 2025, Pages: ?
ISSN:1439-0973
DOI:10.1007/s15010-025-02689-4
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s15010-025-02689-4
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Author Notes:Hannah Nürnberg, Claudia Maria Denkinger, Tabea Krause, Lars Oetken, Sophie Rauer, Amelie Rapp, Lisa Marie Kern, Torsten Hoppe-Tichy, Tilman Schöning, Elham Khatamzas, Benedict Morath
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Summary:Penicillin allergy is the most frequently reported allergy in hospitalized patients, although rarely confirmed. Given the negative outcomes associated with incorrect penicillin allergy diagnoses, implementation of programmatic delabeling strategies is important for successful antibiotic stewardship. This systematic review evaluates the effectiveness of different delabeling strategies and highlights elements and settings that facilitate or constrict their implementation.
Item Description:Gesehen am 12.03.2026
Physical Description:Online Resource
ISSN:1439-0973
DOI:10.1007/s15010-025-02689-4

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