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The German Cancer Consortium (DKTK) multi-center prospective phase 1/2 68Ga-PSMA-11 PET-imaging trial in newly-diagnosed high-risk prostate cancer: safety and diagnostic accuracy compared to histopathology and their impact on patient management

Clinically accurate detection of prostate cancer (PCa) metastases is crucial for management of high-risk PCa patients scheduled for radical prostatectomy. We determine the safety and diagnostic accuracy of pre-operative 68Ga-PSMA-11 PET/CT imaging in newly diagnosed high-risk PCa and assess its impa...

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Main Authors: Giesel, Frederik L. (Author) , Körber, Stefan A. (Author) , Hadaschik, Boris (Author) , Kiefer, Selina (Author) , Schwarzenboeck, Sarah (Author) , Rahbar, Kambiz (Author) , Derlin, Thorsten (Author) , Grott, Christoph A. (Author) , Heck, Matthias (Author) , Jilg, Cordula (Author) , Meyer, Philipp T. (Author) , Ruf, Juri (Author) , Schmidt, Karl (Author) , Kotzerke, Joerg (Author) , la Fougère, Christian (Author) , Reischl, Gerald (Author) , Virgolini, Irene (Author) , Herrmann, Ken (Author) , Burger, Irene A. (Author) , Lorenzini, Theo (Author) , Werner, Martin (Author) , Stenzinger, Albrecht (Author) , Schwamborn, Kristina (Author) , Radtke, Jan Philipp (Author) , Hohenfellner, Markus (Author) , Debus, Jürgen (Author) , Weber, Wolfgang A. (Author) , Haberkorn, Uwe (Author) , Kopka, Klaus (Author) , Eiber, Matthias (Author)
Format: Article (Journal)
Language:English
Published: 2026
In: European journal of nuclear medicine and molecular imaging
Year: 2026, Volume: 53, Pages: 2994-3006
ISSN:1619-7089
DOI:10.1007/s00259-025-07540-4
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00259-025-07540-4
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Author Notes:Frederik L. Giesel, Stefan A. Koerber, Boris Hadaschik, Selina Kiefer, Sarah Schwarzenboeck, Kambiz Rahbar, Thorsten Derlin, Christoph A. Grott, Matthias Heck, Cordula Jilg, Philipp T. Meyer, Juri Ruf, Karl Schmidt, Joerg Kotzerke, Christian la Fougère, Gerald Reischl, Irene Virgolini, Ken Herrmann, Irene A. Burger, Theo Lorenzini, Martin Werner, Albrecht Stenzinger, Kristina Schwamborn, Jan Philipp Radtke, Markus Hohenfellner, Juergen Debus, Wolfgang A. Weber, Uwe Haberkorn, Klaus Kopka, Matthias Eiber 68Ga-PSMA-11 DKTK trial contributors
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Summary:Clinically accurate detection of prostate cancer (PCa) metastases is crucial for management of high-risk PCa patients scheduled for radical prostatectomy. We determine the safety and diagnostic accuracy of pre-operative 68Ga-PSMA-11 PET/CT imaging in newly diagnosed high-risk PCa and assess its impact on patient management.
Item Description:Veröffentlicht: 15 November 2025
Im Text ist "68" hochgestellt
Gesehen am 29.04.2026
Physical Description:Online Resource
ISSN:1619-7089
DOI:10.1007/s00259-025-07540-4

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