Long-term dynamic virological response patterns and clinical outcomes in hepatitis B virus-related cirrhosis: a real-world 10-year cohort study

The long-term clinical outcomes of patients with hepatitis B virus (HBV)-related cirrhosis receiving nucleos(t)ide analog (NA) therapy according to virological response patterns remain inadequately defined. This study aimed to investigate the association between virological response patterns and cli...

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Main Authors: Wang, Yuwei (Author) , Li, Yaxin (Author) , Yu, Yueyang (Author) , Lyu, Lingna (Author) , Liang, Xueying (Author) , Li, Yangjie (Author) , He, Yanglan (Author) , Liu, Yanna (Author) , Jin, Keke (Author) , Fan, Chunlei (Author) , Wu, Yanjing (Author) , Wang, Shanshan (Author) , Dooley, Steven (Author) , Han, Ying (Author) , Ding, Huiguo (Author)
Format: Article (Journal)
Language:English
Published: February 25, 2026
In: Journal of clinical and translational hepatology
Year: 2026, Pages: 1-11
ISSN:2310-8819
DOI:10.14218/JCTH.2025.00683
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.14218/JCTH.2025.00683
Verlag, kostenfrei, Volltext: https://www.xiahepublishing.com/m/2310-8819/JCTH-2025-00683
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Author Notes:Yuwei Wang, Yaxin Li, Yueyang Yu, Lingna Lyu, Xueying Liang, Yangjie Li, Yanglan He, Yanna Liu, Keke Jin, Chunlei Fan, Yanjing Wu, Shanshan Wang, Steven Dooley, Ying Han and Huiguo Ding
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Summary:The long-term clinical outcomes of patients with hepatitis B virus (HBV)-related cirrhosis receiving nucleos(t)ide analog (NA) therapy according to virological response patterns remain inadequately defined. This study aimed to investigate the association between virological response patterns and clinical outcomes in a large, long-term, real-world cohort.
Item Description:Gesehen am 17.03.2026
Physical Description:Online Resource
ISSN:2310-8819
DOI:10.14218/JCTH.2025.00683