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High resolution genome-wide SNP array analyses on matched colorectal-based lung and brain metastases

Colorectal-based brain metastasis formation is a rare and late event in colorectal cancer (CRC) patients and is associated with poor survival. Compared with other metastatic sites, the knowledge about copy number variation (CNV) in brain metastases is still very limited. To get more information abou...

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Bibliographic Details
Main Authors: Brandt, Vivian-Pascal (Author) , Sander, Carolin (Author) , Holland, Lydia (Author) , Koschny, Ronald (Author) , Müller, Wolf C. (Author) , Bläker, Hendrik (Author) , Nestler, Ulf (Author) , Güresir, Erdem (Author) , Holland, Heidrun (Author)
Format: Article (Journal)
Language:English
Published: 30 January 2026
In: Journal of cancer research and clinical oncology
Year: 2026, Volume: 152, Issue: 2, Pages: 1-11
ISSN:1432-1335
DOI:10.1007/s00432-026-06427-7
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00432-026-06427-7
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Author Notes:Vivian-Pascal Brandt, Carolin Sander, Lydia Holland, Ronald Koschny, Wolf C. Müller, Hendrik Bläker, Ulf Nestler, Erdem Güresir, Heidrun Holland
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Summary:Colorectal-based brain metastasis formation is a rare and late event in colorectal cancer (CRC) patients and is associated with poor survival. Compared with other metastatic sites, the knowledge about copy number variation (CNV) in brain metastases is still very limited. To get more information about CNVs, we applied SNP array to analyze chromosomal regions with a higher density of SNP markers.
Item Description:Gesehen am 20.03.2026
Physical Description:Online Resource
ISSN:1432-1335
DOI:10.1007/s00432-026-06427-7

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