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Development of novel proline- and pipecolic acid-based allosteric inhibitors of dengue and Zika virus NS2B/NS3 protease

Background: In this study, we report a novel series of proline- and pipecolic acid-based small molecules designed as allosteric inhibitors of the NS2B...

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Bibliographic Details
Main Authors: Starvaggi, Josè (Author) , Chio, Carla Di (Author) , Lang, Johannes (Author) , Belgiovine, Valentina (Author) , Trisciuzzi, Daniela (Author) , Previti, Santo (Author) , Klein, Christian D. (Author) , Nicolotti, Orazio (Author) , Maro, Salvatore Di (Author) , Zappalà, Maria (Author) , Ettari, Roberta (Author)
Format: Article (Journal)
Language:English
Published: 2026
In: Pharmaceuticals
Year: 2026, Volume: 19, Issue: 1, Pages: 1-25
ISSN:1424-8247
DOI:10.3390/ph19010024
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.3390/ph19010024
Verlag, kostenfrei, Volltext: https://www.mdpi.com/1424-8247/19/1/24
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Author Notes:Josè Starvaggi, Carla Di Chio, Johannes Lang, Valentina Belgiovine, Daniela Trisciuzzi, Santo Previti, Christian Klein, Orazio Nicolotti, Salvatore Di Maro, Maria Zappalà and Roberta Ettari
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Summary:Background: In this study, we report a novel series of proline- and pipecolic acid-based small molecules designed as allosteric inhibitors of the NS2B...
Item Description:Gesehen am 23.03.2026
Physical Description:Online Resource
ISSN:1424-8247
DOI:10.3390/ph19010024

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