Time to colonoscopy after a positive FIT result matters
Screening by fecal immunochemical test (FIT) has become the most widely used approach to colorectal cancer (CRC) screening globally.1 High adherence to FIT use and timely colonoscopic follow-up of positive results are crucial for the effectiveness of FIT-based screening. Several studies from differe...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) Editorial |
| Language: | English |
| Published: |
February 13, 2026
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| In: |
Gut
Year: 2026, Pages: 1-2 |
| ISSN: | 1468-3288 |
| DOI: | 10.1136/gutjnl-2025-337926 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1136/gutjnl-2025-337926 Verlag, lizenzpflichtig, Volltext: https://gut.bmj.com/content/early/2026/02/13/gutjnl-2025-337926 
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| Author Notes: | Hermann Brenner, Idris Ola, Sigrid V. Carlsson, Teresa Seum, Michael Hoffmeister |
| Summary: | Screening by fecal immunochemical test (FIT) has become the most widely used approach to colorectal cancer (CRC) screening globally.1 High adherence to FIT use and timely colonoscopic follow-up of positive results are crucial for the effectiveness of FIT-based screening. Several studies from different countries have reported that delays of follow-up colonoscopies by 3,2 6,3 ,4 59 or 126 months or longer went along with increased CRC risk.2-6 By contrast, in a recent large-scale nationwide study from France, which included 373 114 FIT positive individuals, Grancher et al did not find any increase in CRC prevalence at follow-up colonoscopies conducted up to 2 years from a positive FIT.7 The authors argued that time to follow-up colonoscopy may be of limited relevance given the many years it takes for CRC development. - - However, the trend in observed CRC prevalence with increasing time interval between positive FIT result and follow-up colonoscopy exclusively derived from a screening management database is not a good indicator for the consequences … |
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| Item Description: | Gesehen am 24.03.2026 |
| Physical Description: | Online Resource |
| ISSN: | 1468-3288 |
| DOI: | 10.1136/gutjnl-2025-337926 |