Trends and associated factors of late-stage HIV diagnosis among heterosexuals in the Netherlands between 2012 and 2022: an analysis of national surveillance data

Objectives - Late-stage HIV diagnoses among heterosexuals remain a problem in Europe, yet little is known about its risk factors. We aimed to identify the trends and factors associated with late-stage HIV diagnosis among heterosexuals in the Netherlands. - Methods - We used national HIV surveillance...

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Main Authors: Paske, Karlijn S. te (Author) , Brand, Jean-Marie (Author) , Delsing, Corine (Author) , van den Elshout, Mark (Author) , Hoornenborg, Elske (Author) , Rokx, Casper (Author) , Schippers, Emile F (Author) , Twisk, Denise E (Author) , Hontelez, Jan (Author)
Format: Article (Journal)
Language:English
Published: March 2026
In: International journal of infectious diseases
Year: 2026, Volume: 164, Pages: 1-7
ISSN:1878-3511
DOI:10.1016/j.ijid.2025.108324
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.ijid.2025.108324
Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S1201971225005417
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Author Notes:Karlijn S te Paske, Jean-Marie Brand, Corine Delsing, Mark van den Elshout, Elske Hoornenborg, Casper Rokx, Emile F Schippers, Denise E Twisk, Jan Hontelez, on behalf of the ATHENA observational HIV cohort
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Summary:Objectives - Late-stage HIV diagnoses among heterosexuals remain a problem in Europe, yet little is known about its risk factors. We aimed to identify the trends and factors associated with late-stage HIV diagnosis among heterosexuals in the Netherlands. - Methods - We used national HIV surveillance data and included individuals diagnosed between 2012 and 2022, with heterosexual contact as the suspected transmission route. We applied descriptive statistics and logistic regression analyses. - Results - Of 1637 HIV diagnoses among heterosexuals, 932 (57%) were late-stage disease. The proportion of late-stage diagnoses was stable during 2012-2022 (range 51-62%). Significant risk factors for late-stage diagnosis were male sex (adjusted odds ratio [AOR] = 1.72; 95% confidence interval [CI] = 1.40-2.13), older age (every 10-year increase: AOR = 1.48; 95% CI = 1.34-1.62), being born in Africa (AOR = 2.21; 95% CI = 1.70-2.88), and Asia (AOR = 2.93; 95% CI = 1.88-4.65). People born in eastern Europe approached significance (AOR = 1.70; 95% CI = 0.97-3.05). Most late-stage diagnoses occurred in hospitals. - Conclusions - The proportion of late-stage HIV diagnoses remains high among heterosexuals in the Netherlands. Men; older people; and those born in Africa, Asia, and eastern Europe were associated with late-stage diagnosis.
Item Description:Gesehen am 25.03.2026
Physical Description:Online Resource
ISSN:1878-3511
DOI:10.1016/j.ijid.2025.108324