Safety of high dose bedaquiline treatment in patients with extensively drug-resistant tuberculosis
Extract: Bedaquiline (Bdq) was authorised for the treatment of multidrug-resistant (MDR) tuberculosis (TB) in 2014 in Europe. It is part of the preferred BPaLM regimen (Bdq, pretomanid, linezolid (Lzd), moxifloxacin (Mfx)), of individualised MDR-TB treatment and new MDR-TB regimens recommended by th...
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| Autori principali: | , , , , , , , , , , , , , , |
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| Natura: | Article (Journal) Editorial |
| Lingua: | inglese |
| Pubblicazione: |
2026
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| In: |
The European respiratory journal
Year: 2026, Volume: 67, Fascicolo: 1, Pages: 1-5 |
| ISSN: | 1399-3003 |
| DOI: | 10.1183/13993003.01496-2025 |
| Accesso online: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1183/13993003.01496-2025 Verlag, lizenzpflichtig, Volltext: https://publications.ersnet.org/content/erj/67/1/2501496 |
| Note sull'autore: | Manuel Peterka, David Krieger, Elham Khatamzas, Claudia M. Denkinger, Niklas Köhler, Christoph Lange, Martin Macholz, Christoph Lübbert, Simon Daller, Michael Knappik, Martin Kuhns, Brit Häcker, Silke Polsfuß, Torsten Bauer and Ralf Otto-Knapp |
| Riassunto: | Extract: Bedaquiline (Bdq) was authorised for the treatment of multidrug-resistant (MDR) tuberculosis (TB) in 2014 in Europe. It is part of the preferred BPaLM regimen (Bdq, pretomanid, linezolid (Lzd), moxifloxacin (Mfx)), of individualised MDR-TB treatment and new MDR-TB regimens recommended by the recently updated World Health Organization guidelines [1]. Most trials aiming to develop new regimens for drug-resistant TB include Bdq, making it the most important drug at present. |
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| Descrizione del documento: | Gesehen am 17.04.2026 |
| Descrizione fisica: | Online Resource |
| ISSN: | 1399-3003 |
| DOI: | 10.1183/13993003.01496-2025 |