Interleukin-6 to identify mildly injured patients in the trauma resuscitation room - a clinical feasibility study
Overtriage in the trauma resuscitation room (TRR) is often a consequence of admission based solely on trauma mechanism criteria. As interleukin-6 (IL-6) can assess injury severity in critically injured patients, the hypothesis of this study was that IL-6 can differentiate upon admission between mild...
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| Main Authors: | , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
24 March 2026
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| In: |
European journal of trauma and emergency surgery
Year: 2026, Volume: 52, Pages: 1-14 |
| ISSN: | 1863-9941 |
| DOI: | 10.1007/s00068-026-03160-1 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00068-026-03160-1
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| Author Notes: | Tim Niklas Bewersdorf, Marc Wimmer, Erik Popp, Jan Streblow, Lukas Baumann, Christine Leowardi, Stephan Stein, Gerhard Schmidmaier, Tobias Grossner |
| Summary: | Overtriage in the trauma resuscitation room (TRR) is often a consequence of admission based solely on trauma mechanism criteria. As interleukin-6 (IL-6) can assess injury severity in critically injured patients, the hypothesis of this study was that IL-6 can differentiate upon admission between mild (Injury Severity Score (ISS) 0-8) and moderate (ISS 9-15) trauma and that the parameter correlates with injury severity in lower injury severity groups (ISS < 16) during the first 24 h. Subsequently, we evaluated the ability to define IL-6 cut-off values with an adequate sensitivity, specificity, and negative predictive value to distinguish between moderate and mild injuries. |
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| Item Description: | Veröffentlicht: 24. März 2026 Gesehen am 23.04.2026 |
| Physical Description: | Online Resource |
| ISSN: | 1863-9941 |
| DOI: | 10.1007/s00068-026-03160-1 |