Health-related quality of life in long-term prostate cancer survivors who received hormone therapy: a scoping review

Many men now live for many years after prostate cancer diagnosis. Hormone therapy is one of the main treatments available, especially when the cancer is advanced, but its long-term effects on daily life are not well understood. In this review, we looked at studies of men who survived at least 5 year...

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Main Authors: Basbous, Maya (Author) , Yang, Keyi (Author) , Arndt, Volker (Author) , Thong, Melissa S. Y. (Author)
Format: Article (Journal)
Language:English
Published: 26 February 2026
In: Current oncology
Year: 2026, Volume: 33, Issue: 3, Pages: 1-15
ISSN:1718-7729
DOI:10.3390/curroncol33030137
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/curroncol33030137
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/1718-7729/33/3/137
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Author Notes:Maya Basbous, Keyi Yang, Volker Arndt and Melissa S.Y. Thong
Description
Summary:Many men now live for many years after prostate cancer diagnosis. Hormone therapy is one of the main treatments available, especially when the cancer is advanced, but its long-term effects on daily life are not well understood. In this review, we looked at studies of men who survived at least 5 years after prostate cancer diagnosis and had received hormone therapy. The findings show that, compared with men treated only with local therapies, such as surgery or radiation, those who had hormone therapy often reported poorer overall health, more physical and emotional difficulties, lower energy, and greater problems with social life. They also experienced more bowel, urinary, and sexual problems. In addition, very little research has followed men beyond 15 years. These insights highlight the need for clearer discussions with patients about long-term effects and for future studies to better understand how different hormone treatments affect long-term quality of life.
Item Description:Veröffentlicht: 26. Februar 2026
Gesehen am 29.04.2026
Physical Description:Online Resource
ISSN:1718-7729
DOI:10.3390/curroncol33030137