How strong is a mitochondrial targeting signal?

In this issue, Yan et al. show that mitochondrial targeting signals (presequences) vary widely in import strength. Using the quantitative MitoLuc and PotLuc assays, they dissect multiple parameters of protein import and reveal how presequence features influence mitochondrial targeting efficiency and...

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Bibliographic Details
Main Authors: Peselj, Carlotta (Author) , Vögtle, Friederike-Nora (Author)
Format: Article (Journal)
Language:English
Published: 6 April 2026
In: The journal of cell biology
Year: 2026, Volume: 225, Issue: 4, Pages: 1-3
ISSN:1540-8140
DOI:10.1083/jcb.202603036
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1083/jcb.202603036
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Author Notes:Carlotta Peselj and F.-Nora Vögtle
Description
Summary:In this issue, Yan et al. show that mitochondrial targeting signals (presequences) vary widely in import strength. Using the quantitative MitoLuc and PotLuc assays, they dissect multiple parameters of protein import and reveal how presequence features influence mitochondrial targeting efficiency and stress sensitivity.
Item Description:Veröffentlicht: 24. März 2026
Gesehen am 30.04.2026
Physical Description:Online Resource
ISSN:1540-8140
DOI:10.1083/jcb.202603036