How strong is a mitochondrial targeting signal?

In this issue, Yan et al. show that mitochondrial targeting signals (presequences) vary widely in import strength. Using the quantitative MitoLuc and PotLuc assays, they dissect multiple parameters of protein import and reveal how presequence features influence mitochondrial targeting efficiency and...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Peselj, Carlotta (Auteur) , Vögtle, Friederike-Nora (Auteur)
Format: Article (Journal)
Langue:anglais
Publié: 6 April 2026
In: The journal of cell biology
Year: 2026, Volume: 225, Numéro: 4, Pages: 1-3
ISSN:1540-8140
DOI:10.1083/jcb.202603036
Accès en ligne:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1083/jcb.202603036
Accéder au texte intégral
Notes sur l'auteur:Carlotta Peselj and F.-Nora Vögtle
Description
Résumé:In this issue, Yan et al. show that mitochondrial targeting signals (presequences) vary widely in import strength. Using the quantitative MitoLuc and PotLuc assays, they dissect multiple parameters of protein import and reveal how presequence features influence mitochondrial targeting efficiency and stress sensitivity.
Description:Veröffentlicht: 24. März 2026
Gesehen am 30.04.2026
Description matérielle:Online Resource
ISSN:1540-8140
DOI:10.1083/jcb.202603036