Gold-catalyzed regioselective remote B(9)-H activation of o-carboranes with silylenynones: access to B(9)-α-furylsilyl-o-carboranes
The gold-catalyzed regioselective remote B(9)-H functionalization of o-carboranes through regioselective insertion of α-furyl silyl gold carbenes generated from silylenynones into the B(9)-H bond of o-carboranes offers facile and atom-economical access to various B(9)-α-furylsilyl-o-carboranes in mo...
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| Auteurs principaux: | , , , , , , |
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| Format: | Article (Journal) |
| Langue: | anglais |
| Publié: |
10 April 2026
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| In: |
Organic letters
Year: 2026, Volume: 28, Numéro: 14, Pages: 4384-4389 |
| ISSN: | 1523-7052 |
| DOI: | 10.1021/acs.orglett.6c00507 |
| Accès en ligne: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1021/acs.orglett.6c00507 Verlag, lizenzpflichtig, Volltext: https://pubs.acs.org/doi/10.1021/acs.orglett.6c00507?src=getftr&utm_source=clarivate&getft_integrator=clarivate 
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| Notes sur l'auteur: | Yue Hao, Huiyuan Zheng, Chengrui Hang, Ling Zhi, A. Stephen K. Hashmi, Guanghui Wang, Ximei Zhao |
| Résumé: | The gold-catalyzed regioselective remote B(9)-H functionalization of o-carboranes through regioselective insertion of α-furyl silyl gold carbenes generated from silylenynones into the B(9)-H bond of o-carboranes offers facile and atom-economical access to various B(9)-α-furylsilyl-o-carboranes in moderate to good yields (up to 88%) with excellent regioselectivities. This method can also be expanded to the selective B-H functionalization of m-carboranes. The synthetic potential of this methodology is exemplified by gram-scale experiments and synthetic transformations of the products. |
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| Description: | Online verfügbar: 27. März 2026 Gesehen am 02.06.2026 |
| Description matérielle: | Online Resource |
| ISSN: | 1523-7052 |
| DOI: | 10.1021/acs.orglett.6c00507 |