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Thoracolumbar fascia thickness and body mass index as predictors of pain sensitivity: a single-blinded experimental hypertonic saline study

The thoracolumbar fascia (TLF) is a key connective tissue structure that is involved in biomechanics of the lumbar spine and nociceptive processing. Growing evidence indicates that body mass index (BMI) is associated with connective-tissue remodeling, that may influence pain sensitivity and may thus...

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Main Authors: Axmann, Philipp (Author) , Jung, Carla (Author) , Darwich, Ali (Author) , Vadgaonkar, Aditya (Author) , Dally, Franz (Author) , Schulz, Steffen (Author) , Blümke, Alexander Felix (Author) , Bludau, Frederic (Author) , Gravius, Sascha (Author) , Schilder, Andreas (Author)
Format: Article (Journal)
Language:English
Published: May 2026
In: BMC musculoskeletal disorders
Year: 2026, Volume: 27, Pages: 1-8
ISSN:1471-2474
DOI:10.1186/s12891-026-09992-7
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12891-026-09992-7
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Author Notes:Philipp Axmann, Carla Jung, Ali Darwich, Aditya Vadgaonkar, Franz-Joseph Dally, Steffen Schulz, Alexander Blümke, Frederic Bludau, Sascha Gravius and Andreas Schilder
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Summary:The thoracolumbar fascia (TLF) is a key connective tissue structure that is involved in biomechanics of the lumbar spine and nociceptive processing. Growing evidence indicates that body mass index (BMI) is associated with connective-tissue remodeling, that may influence pain sensitivity and may thus contribute to musculoskeletal pain. However, the extent to which BMI-related differences in fascia morphology predict pain responses under controlled experimental conditions remains insufficiently understood. This study investigated thoracolumbar fascia thickness and BMI as predictors of pain sensitivity using a single-blinded experimental hypertonic saline pain model.
Item Description:Online veröffentlicht: 22. Mai 2026, Artikelversion: 27. Mai 2026
Gesehen am 09.06.2026
Physical Description:Online Resource
ISSN:1471-2474
DOI:10.1186/s12891-026-09992-7

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