The current landscape of therapeutic vaccination approaches for treatment of HPV-dependent malignancies
This review provides an overview of current therapeutic human papillomavirus (HPV) vaccination approaches. We review important criteria for their development, and present vaccines currently being actively followed in clinical trials, for precursor lesions or established cancers. Subsequently, we lis...
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| Autori principali: | , , |
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| Natura: | Article (Journal) |
| Lingua: | inglese |
| Pubblicazione: |
15 April 2026
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| In: |
npj vaccines
Year: 2026, Volume: 11, Pages: 1-23 |
| ISSN: | 2059-0105 |
| DOI: | 10.1038/s41541-026-01426-8 |
| Accesso online: | Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41541-026-01426-8 Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41541-026-01426-8 
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| Note sull'autore: | Johanne Audouze-Chaud, Ann-Katrin Schlosser & Angelika B. Riemer |
| Riassunto: | This review provides an overview of current therapeutic human papillomavirus (HPV) vaccination approaches. We review important criteria for their development, and present vaccines currently being actively followed in clinical trials, for precursor lesions or established cancers. Subsequently, we list approaches that reached clinical trial stage but were abandoned. Lastly, we discuss promising preclinical studies. We conclude with a brief overview of novel in silico tools developed to enhance vaccine design. |
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| Descrizione del documento: | Veröffentlicht: 15. April 2026 Gesehen am 09.06.2026 |
| Descrizione fisica: | Online Resource |
| ISSN: | 2059-0105 |
| DOI: | 10.1038/s41541-026-01426-8 |