Automated (18F)PSMA-1007 production by a single use cassette-type synthesizer for clinical examination
[18F]PSMA-1007, a positron emission tomography (PET) tracer, specifically targets prostate-specific membrane antigen (PSMA), which is highly expressed in prostate cancer. PSMA-PET is effective especially for regional detection of biochemical recurrence, which significantly affects patient management...
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| Auteurs principaux: | , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Langue: | anglais |
| Publié: |
29 July 2020
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| In: |
EJNMMI radiopharmacy and chemistry
Year: 2020, Volume: 5, Numéro: 1, Pages: 1-17 |
| ISSN: | 2365-421X |
| DOI: | 10.1186/s41181-020-00101-0 |
| Accès en ligne: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s41181-020-00101-0 Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1186/s41181-020-00101-0 
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| Notes sur l'auteur: | Sadahiro Naka, Tadashi Watabe, Kenta Kurimoto, Motohide Uemura, Fumihiko Soeda, Oliver C. Neels, Klaus Kopka, Mitsuaki Tatsumi, Hiroki Kato, Norio Nonomura, Eku Shimosegawa, Jens Cardinale, Frederik L. Giesel and Jun Hatazawa |
| Résumé: | [18F]PSMA-1007, a positron emission tomography (PET) tracer, specifically targets prostate-specific membrane antigen (PSMA), which is highly expressed in prostate cancer. PSMA-PET is effective especially for regional detection of biochemical recurrence, which significantly affects patient management. Herein, we established and optimized a one-step radiolabeling protocol to separate and purify [18F]PSMA-1007 with a CFN-MPS200 synthesizer for clinical application. |
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| Description: | Im Titel steht der Ausdruck 18F in eckiger Klammer, dabei ist die Zahl "18" hochgestellt Gesehen am 01.07.2026 |
| Description matérielle: | Online Resource |
| ISSN: | 2365-421X |
| DOI: | 10.1186/s41181-020-00101-0 |