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Automated (18F)PSMA-1007 production by a single use cassette-type synthesizer for clinical examination

[18F]PSMA-1007, a positron emission tomography (PET) tracer, specifically targets prostate-specific membrane antigen (PSMA), which is highly expressed in prostate cancer. PSMA-PET is effective especially for regional detection of biochemical recurrence, which significantly affects patient management...

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Detalles Bibliográficos
Autores principales: Naka, Sadahiro (Autor) , Watabe, Tadashi (Autor) , Kurimoto, Kenta (Autor) , Uemura, Motohide (Autor) , Soeda, Fumihiko (Autor) , Neels, Oliver C. (Autor) , Kopka, Klaus (Autor) , Tatsumi, Mitsuaki (Autor) , Kato, Hiroki (Autor) , Nonomura, Norio (Autor) , Shimosegawa, Eku (Autor) , Cardinale, Jens (Autor) , Giesel, Frederik L. (Autor) , Hatazawa, Jun (Autor)
Formato: Article (Journal)
Lenguaje:inglés
Publicado: 29 July 2020
In: EJNMMI radiopharmacy and chemistry
Year: 2020, Volumen: 5, Número: 1, Pages: 1-17
ISSN:2365-421X
DOI:10.1186/s41181-020-00101-0
Acceso en línea:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s41181-020-00101-0
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1186/s41181-020-00101-0
Enlace del recurso
Notas de Autor:Sadahiro Naka, Tadashi Watabe, Kenta Kurimoto, Motohide Uemura, Fumihiko Soeda, Oliver C. Neels, Klaus Kopka, Mitsuaki Tatsumi, Hiroki Kato, Norio Nonomura, Eku Shimosegawa, Jens Cardinale, Frederik L. Giesel and Jun Hatazawa
Descripción
Sumario:[18F]PSMA-1007, a positron emission tomography (PET) tracer, specifically targets prostate-specific membrane antigen (PSMA), which is highly expressed in prostate cancer. PSMA-PET is effective especially for regional detection of biochemical recurrence, which significantly affects patient management. Herein, we established and optimized a one-step radiolabeling protocol to separate and purify [18F]PSMA-1007 with a CFN-MPS200 synthesizer for clinical application.
Notas:Im Titel steht der Ausdruck 18F in eckiger Klammer, dabei ist die Zahl "18" hochgestellt
Gesehen am 01.07.2026
Descripción Física:Online Resource
ISSN:2365-421X
DOI:10.1186/s41181-020-00101-0

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