Temporal dynamics of suspiciousness and hallucinations in clinical high risk and first episode psychosis

The objective of the current study is to elucidate the temporal dynamics of suspiciousness and hallucinations as they occur in daily life in the early stages of psychosis. Their prevalence and co-occurrence, as well as their temporal relation to affect and delusions, were compared between patients w...

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Autori principali: Hermans, Karlijn (Autore) , van der Steen, Yori (Autore) , Kasanova, Zuzana (Autore) , Winkel, Ruud van (Autore) , Reininghaus, Ulrich (Autore) , Lataster, Tineke (Autore) , Bechdolf, Andreas (Autore) , Gimpel-Drees, Judith (Autore) , Wagner, Michael (Autore) , Myin-Germeys, Inez (Autore)
Natura: Article (Journal)
Lingua:inglese
Pubblicazione: August 2020
In: Psychiatry research
Year: 2020, Volume: 290, Pages: 1-8
ISSN:1872-7123
DOI:10.1016/j.psychres.2020.113039
Accesso online:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.psychres.2020.113039
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0165178119324783
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Note sull'autore:Karlijn Hermans, Yori van der Steen, Zuzana Kasanova, Ruud van Winkel, Ulrich Reininghaus, Tineke Lataster, Andreas Bechdolf, Judith Gimpel-Drees, Michael Wagner, Inez Myin-Germeys
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Riassunto:The objective of the current study is to elucidate the temporal dynamics of suspiciousness and hallucinations as they occur in daily life in the early stages of psychosis. Their prevalence and co-occurrence, as well as their temporal relation to affect and delusions, were compared between patients with a first psychotic episode (FEP) and individuals at clinical high risk for psychosis (CHRp). The Experience Sampling Method was used to investigate suspiciousness and hallucinatory experiences, delusions, and affect at semi-random moments throughout six days in 33 CHRp and 34 FEP. Overall, 91% of CHRp and 59% of FEP reported suspiciousness, and 24% and 39% reported hallucinations, respectively. Hallucinations almost always co-occurred with suspiciousness, whereas suspiciousness was often present without hallucinations. Suspicious episodes in CHRp occurred with marked increases in delusional intensity, while hallucinatory experiences were mostly absent. In FEP, a decrease of positive affect preceded suspicious episodes, while an increase of negative affect preceded hallucinatory episodes. Our results indicated the presence of a delusional mood (atmosphere) in CHRp as an experience in itself, without co-occurring or following hallucinations, thus refuting the anomalous experience hypothesis of psychosis. The co-occurrence of hallucinations, on the other hand, indicates a more severe stage of symptomatology.
Descrizione del documento:Gesehen am 11.08.2026
Descrizione fisica:Online Resource
ISSN:1872-7123
DOI:10.1016/j.psychres.2020.113039