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Patch test results with the European Baseline Series, 2021/2022: joint European results of the ESSCAA and the EBSB working groups of the ESCD, and the GEIDACC

BACKGROUND: Patch test results obtained with the European Baseline Series (EBS) in its current version serve both contact allergy surveillance and (re-)assessing the diagnostic value of EBS allergens. - OBJECTIVES: To present results of current EBS patch testing, obtained in 59 departments in 14 Eur...

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Hauptverfasser: Uter, Wolfgang (Verfasst von) , Wilkinson, S. Mark (Verfasst von) , Aerts, Olivier (Verfasst von) , Bauer, Andrea (Verfasst von) , Borrego, Leopoldo (Verfasst von) , Brans, Richard (Verfasst von) , Buhl, Timo (Verfasst von) , Dickel, Heinrich (Verfasst von) , Dugonik, Aleksandra (Verfasst von) , Filon, Francesca Larese (Verfasst von) , Arnau, Ana Giménez (Verfasst von) , Patruno, Cataldo (Verfasst von) , Pónyai, Györgyi (Verfasst von) , Gregoriou, Stamatis (Verfasst von) , Schubert, Steffen (Verfasst von) , Simon, Dagmar (Verfasst von) , Stingeni, Luca (Verfasst von) , Valiukevičienė, Skaidra (Verfasst von) , Weisshaar, Elke (Verfasst von) , Werfel, Thomas (Verfasst von) , Gonçalo, Margarida (Verfasst von) , Schuttelaar, Marie L.A. (Verfasst von)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: July 2026
In: Contact dermatitis
Year: 2026, Jahrgang: 95, Heft: 1, Pages: 17-32
ISSN:1600-0536
DOI:10.1111/cod.70134
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1111/cod.70134
Volltext
Verfasserangaben:Wolfgang Uter, S. Mark Wilkinson, Olivier Aerts, Andrea Bauer, Leopoldo Borrego, Richard Brans, Timo Buhl, Heinrich Dickel, Aleksandra Dugonik, Francesca Larese Filon, Ana Giménez Arnau, Cataldo Patruno, Györgyi Pónyai, Stamatis Gregoriou, Steffen Schubert, Dagmar Simon, Luca Stingeni, Skaidra Valiukevičienė, Elke Weisshaar, Thomas Werfel, Margarida Gonçalo, Marie-L. A. Schuttelaar, ESSCAA and EBSB ESCD Working Groups, and the GEIDACC
Beschreibung
Zusammenfassung:BACKGROUND: Patch test results obtained with the European Baseline Series (EBS) in its current version serve both contact allergy surveillance and (re-)assessing the diagnostic value of EBS allergens. - OBJECTIVES: To present results of current EBS patch testing, obtained in 59 departments in 14 European countries during 2021 and 2022. - METHODS: Anonymised or pseudonymised individual data, and partly aggregated results, on demographic/clinical characteristics and patch test results with the EBS were prospectively collected, centrally pooled, and retrospectively analysed. - RESULTS: In 2021 and 2022, 18 832 patients were patch tested with the EBS. Sensitization to nickel remained most common (18.85 (18.29-19.43)% positivity (95% confidence interval)). Fragrance mix I and Myroxylon pereirae resin yielded very similar results with 6.39 (6.04-6.76)% and 6.5 (6.15-6.87)% positivity, respectively. Concerning preservatives, methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) 0.02% aq. yielded 5.52 (5.11-5.96)% and MI 0.2% aq. yielded 5.28 (4.94-5.64)% positives. Testing formaldehyde 2% aq. identified almost one percentage point more positive reactions than 1% aq. (2.05 (1.81-2.32)% vs. 1.22 (0.99-1.48)). Positive reactions to the recently added allergens were most frequently seen to propolis (5.47 (5.12-5.84)%) and 2-hydroxyethyl methacrylate (3.63 (3.32-3.96)%). - CONCLUSIONS: Compared to the previous reporting period, surveillance results with the EBS were mostly stable. The results regarding Quaternium 15 (0.4 (0.29-0.53)% positives) justified its exclusion from the 2023 EBS version.
Beschreibung:Online veröffentlicht: 12. März 2026
Gesehen am 12.08.2026
Beschreibung:Online Resource
ISSN:1600-0536
DOI:10.1111/cod.70134

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