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Identifying modifiable perioperative risk factors for wound healing complications after immediate autologous breast reconstruction

Background - Autologous breast reconstruction (ABR) offers superior aesthetics but carries significant risks of wound healing complications. We aimed to identify modifiable perioperative factors associated with these complications to optimize surgical outcomes. - Methods - We analyzed the ACS-NSQIP...

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Autori principali: Schaschinger, Thomas (Autore) , Niederegger, Tobias (Autore) , Brandt, Jule (Autore) , Knoedler, Samuel (Autore) , Koçak, Elif (Autore) , Sofo, Giuseppe (Autore) , Öztürk, Mahmut (Autore) , Mayer, Simon Andreas (Autore) , Palackic, Alen (Autore) , Orgill, Dennis P. (Autore) , Panayi, Adriana C. (Autore) , Hundeshagen, Gabriel (Autore)
Natura: Article (Journal)
Lingua:inglese
Pubblicazione: July 2026
In: The American journal of surgery
Year: 2026, Volume: 257, Pages: 1-7
ISSN:1879-1883
DOI:10.1016/j.amjsurg.2026.117003
Accesso online:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.amjsurg.2026.117003
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0002961026001868
Testo
Note sull'autore:Thomas Schaschinger, Tobias Niederegger, Jule Brandt, Samuel Knoedler, Elif Koçak, Giuseppe Sofo, Mahmut Öztürk, Simon Mayer, Alen Palackic, Dennis P. Orgill, Adriana C. Panayi, Gabriel Hundeshagen
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Riassunto:Background - Autologous breast reconstruction (ABR) offers superior aesthetics but carries significant risks of wound healing complications. We aimed to identify modifiable perioperative factors associated with these complications to optimize surgical outcomes. - Methods - We analyzed the ACS-NSQIP database (2011-2022) for patients undergoing immediate ABR. Multivariable regression identified independent associations with 30-day wound complications. - Results - Among 7489 patients, wound complications occurred 634 times: superficial surgical site infection (SSSI, n = 358), deep incisional infection (DII, n = 87), dehiscence (n = 126), and organ space infection (OSI, n = 63). Higher BMI was significantly associated with all wound complication types (OR 1.1; p ≤ 0.001). Smoking was independently associated with SSSI (OR 1.6; p = 0.024) and DII (OR 2.3; p = 0.033). Diabetes (OR 3.3; p < 0.001) and dyspnea (OR 3.6; p = 0.022) were significantly associated with increased OSI risk. Wound class >1 was associated with SSSI (OR 1.5) and DII (OR 2.4). - Conclusion - BMI, smoking, and diabetes are critical and potentially modifiable risk factors associated with wound complications in ABR. Preoperative optimization could reduce these adverse events and improve reconstructive success.
Descrizione del documento:Online verfügbar: 21. April 2026, Artikelversion: 28. April 2026
Gesehen am 13.08.2026
Descrizione fisica:Online Resource
ISSN:1879-1883
DOI:10.1016/j.amjsurg.2026.117003

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