Clinical utility of proenkephalin A 119-159 for prediction of worsening renal function and prognosis in patients with sepsis -results of a patient-level meta-analysis
Proenkephalin A 119-159 (penKid) is a functional kidney biomarker inversely correlating with the glomerular filtration rate. We conducted a patient-level meta-analysis to evaluate whether penKid provides additional value to serum creatinine (sCr) for assessing kidney function and outcome in patients...
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| Autori principali: | , , , , , , , , , , , , |
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| Natura: | Article (Journal) |
| Lingua: | inglese |
| Pubblicazione: |
2026
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| In: |
Critical care
Year: 2026, Volume: 30, Pages: 1-6 |
| ISSN: | 1466-609X |
| DOI: | 10.1186/s13054-026-05947-5 |
| Accesso online: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13054-026-05947-5 |
| Note sull'autore: | Birte Arlt, Pietro Caironi, Jennifer Meessen, Oliver Hartmann, Alexandre Mebazaa, Matthieu Legrand, Etienne Gayat, Christian Nusshag, Thorsten Brenner, Pierre François Laterre, Ornella Tinelli, Roberto Latini nad Florian Uhle |
| Riassunto: | Proenkephalin A 119-159 (penKid) is a functional kidney biomarker inversely correlating with the glomerular filtration rate. We conducted a patient-level meta-analysis to evaluate whether penKid provides additional value to serum creatinine (sCr) for assessing kidney function and outcome in patients with sepsis or septic shock. |
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| Descrizione del documento: | Online veröffentlicht: 24. März 2026 Gesehen am 26.08.2026 |
| Descrizione fisica: | Online Resource |
| ISSN: | 1466-609X |
| DOI: | 10.1186/s13054-026-05947-5 |