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Psychometric validation of research domain criteria, general health, and clinical-psychosocial parts of the minimum dataset of the German Center for Mental Health: informing a Delphi process

Objective This study evaluated the latent structure and conceptual validity of the Research Domain Criteria (RDoC), General Health, and Clinical/Psychosocial clusters of the German Center for Mental Health (DZPG) Minimum Data Set (MDS). It aimed to determine whether these clusters represent interpre...

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Main Authors: Förstner, Bernd Rainer (Author) , Böttger, Sarah Jane (Author) , Seegert, Timm (Author) , Kerber, André (Author) , Terhorst, Yannik (Author) , Heinz, Andreas (Author) , Dziobek, Isabel (Author) , Voigt, Babett (Author) , Schneider, Silvia (Author) , Opel, Nils (Author) , Walter, Martin (Author) , Braun, Urs (Author) , Meyer-Lindenberg, Andreas (Author) , Koutsouleris, Nikolaos (Author) , Falkai, Peter (Author) , Schmitz, Norbert (Author) , Fallgatter, Andreas J. (Author) , Sünkel, Ulrike (Author) , Lipinski, Silke (Author) , Rapp, Michael A. (Author) , Tschorn, Mira (Author) , Bauer, Stephanie (Author) , Herpertz, Sabine (Author) , Kling, Philipp (Author) , Kubera, Katharina Maria (Author) , Lenz, Bernd (Author) , Reininghaus, Ulrich (Author) , Rauschenberg, Christian (Author) , Schwarz, Emanuel (Author) , Tost, Heike (Author) , Wilhelm, Maximilian (Author) , Bertsch, Katja (Author)
Format: Article (Journal)
Language:English
Published: 2026
In: European archives of psychiatry and clinical neuroscience
Year: 2026, Pages: 1-20
ISSN:1433-8491
DOI:10.1007/s00406-026-02315-w
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00406-026-02315-w
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Author Notes:Bernd R. Förstner, Sarah Jane Böttger, Timm Seegert, André Kerber, Yannik Terhorst, Andreas Heinz, Isabel Dziobek, Babett Voigt, Silvia Schneider, Nils Opel, Martin Walter, Urs Braun, Andreas Meyer-Lindenberg, Nikolaos Koutsouleris, Peter Falkai, Norbert Schmitz, Andreas J. Fallgatter, Ulrike Sünkel, Silke Lipinski, Michael A. Rapp, Mira Tschorn, MDS Expert Group List
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Summary:Objective This study evaluated the latent structure and conceptual validity of the Research Domain Criteria (RDoC), General Health, and Clinical/Psychosocial clusters of the German Center for Mental Health (DZPG) Minimum Data Set (MDS). It aimed to determine whether these clusters represent interpretable constructs and demonstrate cross-group comparability across clinical and non-clinical populations, providing a data-driven basis for item selection within a Delphi consensus process. Methods Two subsamples were analyzed: a representative sample (N = 2,287) and a clinic-recruited sample (N = 322) from six DZPG sites. Multi-group confirmatory factor analyses tested the latent structure and assessed configural, metric, and scalar measurement invariance between non-clinical vs. clinical/help-seeking groups. Results All three MDS clusters demonstrated excellent baseline model fit (RDoC: CFI = .990, RMSEA = .037; General Health: CFI = .993, RMSEA = .037; Clinical/Psychosocial factors: CFI = .992, RMSEA = .026). Analyses confirmed configural and scalar invariance across all clusters but indicated non-invariance at the metric level for the General Health cluster. Conclusions The results provide initial evidence for the structural validity and cross-group comparability of the RDoC and Clinical/Psychosocial clusters, while indicating limitations regarding metric non-invariance within the General Health cluster. They informed a Delphi consensus process and support the MDS as a scalable framework for diverse populations, particularly relevant for the DZPG’s effort to harmonize mental health data across institutions and contexts.
Item Description:Online veröffentlich: 22. August 2026
Mitglieder der MDS Expert Group List: Vera Birgel, Alice Braun, Christoph Correll, Caroline Cohrdes, Sonja Entringer, Paul Gellert, Melissa Gül Halil, Sven Hädel, Christine Heim, Christine Knaevelsrud, Julia Kraft, Stephan Ripke, Matthias Rose, Henrik Walter, Julia Brailovskaia, Britta Bredenbröcker, Robert Kumsta, Maike Luhmann, Jürgen Margraf, Friederike Räder, Svenja Schaumburg, Sabine Seehagen, Ilona Croy, Katja Lind, Rafael Mikolajczyk, Fabian Rottstädt, Lavinia-Alexandra Steinmann, Stefanie Bauer, Sabine C. Herpertz, Philipp Kling, Katharina Kubera, Bernd Lenz, Ulrich Reininghaus, Christian Rauschenberg, Emanuel Schwarz, Heike Tost, Maximilian Wilhelm, Katja Bertsch, Thomas Ehring, Peter Henningsen, Stefan Leucht, Isabel Maurus, Frank Padberg, Anne Ruef, Gerd Eschweiler, Vanessa Nieratschker, Andreas Stengel, Stephan Zipfel, Myriam Bea, Rüdiger Hannig, Franz-Josef Wagner, Niall Boyce, David Cicero, Bruce Cuthbert, Ophélia Godin, Ute Habel, Marion Leboyer, Wolfgang Lutz, Isabel Maurus, Marcus Mund, Jenni Pacheco, Alizé Rogge, Steven Roose, Marie-Hélène Soto
Gesehen am 31.08.2026
Physical Description:Online Resource
ISSN:1433-8491
DOI:10.1007/s00406-026-02315-w

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