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Clinical utility of sarcoma methylation classifiers in soft tissue sarcoma diagnosis

Soft tissue sarcomas are rare malignant tumors of mesenchymal origin characterized by their heterogeneity and diagnosis is challenging despite integrated histopathology and molecular testing. DNA methylation profiling offers an objective approach for tumor classification, but clinical implementation...

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Autori principali: Osterloh, Justus (Autore) , Reuss, David (Autore) , Deimling, Andreas von (Autore) , Füllgraf, Hannah (Autore) , Heyer, Jannis (Autore) , Kurowski, Konrad (Autore) , Kirchhof, Clara (Autore) , Meiertoberens, Anna (Autore) , Lausch, Ute (Autore) , Schmid, Adrian (Autore) , Eisenhardt, Steffen U. (Autore) , Braig, David (Autore) , Runkel, Alexander (Autore)
Natura: Article (Journal)
Lingua:inglese
Pubblicazione: 6 May 2026
In: Journal of cancer research and clinical oncology
Year: 2026, Volume: 152, Fascicolo: 5, Pages: 1-9
ISSN:1432-1335
DOI:10.1007/s00432-026-06494-w
Accesso online:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00432-026-06494-w
Testo
Note sull'autore:Justus Osterloh, David E. Reuss, Andreas von Deimling, Hannah Füllgraf, Jannis Heyer, Konrad Kurowski, Clara Kirchhof, Anna Meiertoberens, Ute Lausch, Adrian Schmid, Steffen U. Eisenhardt, David Braig, Alexander Runkel
Descrizione
Riassunto:Soft tissue sarcomas are rare malignant tumors of mesenchymal origin characterized by their heterogeneity and diagnosis is challenging despite integrated histopathology and molecular testing. DNA methylation profiling offers an objective approach for tumor classification, but clinical implementation data in soft tissue sarcoma remain limited.
Descrizione del documento:Gesehen am 15.09.2026
Descrizione fisica:Online Resource
ISSN:1432-1335
DOI:10.1007/s00432-026-06494-w

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