SUMO: regulating the regulator
Post-translational modifiers of the SUMO (Small Ubiquitin-related Modifier) family have emerged as key regulators of protein function and fate. While the past few years have seen an enormous increase in knowledge on SUMO enzymes, substrates, and consequences of modification,regulation of SUMO conjug...
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| Weitere Verfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2006
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| In: |
Cell division
Year: 2006, Jahrgang: 1, Heft: 13, Pages: 1-8 |
| ISSN: | 1747-1028 |
| DOI: | 10.1186/1747-1028-1-13 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1186/1747-1028-1-13 Verlag, Volltext: http://webdoc.sub.gwdg.de/pub/med/2007/biomed/2006-melchior.pdf Resolving-System, Volltext: http://dx.doi.org/10.1186/1747-1028-1-13 
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| Verfasserangaben: | Guillaume Bossis and Frauke Melchior |
| Zusammenfassung: | Post-translational modifiers of the SUMO (Small Ubiquitin-related Modifier) family have emerged as key regulators of protein function and fate. While the past few years have seen an enormous increase in knowledge on SUMO enzymes, substrates, and consequences of modification,regulation of SUMO conjugation is far from being understood. This brief review will provide an overview on recent advances concerning (i) the interplay between sumoylation and other posttranslational modifications at the level of individual targets and (ii) global regulation of SUMO conjugation and deconjugation. |
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| Beschreibung: | Online Resource |
| Dokumenttyp: | Systemvoraussetzungen: Acrobat reader. |
| ISSN: | 1747-1028 |
| DOI: | 10.1186/1747-1028-1-13 |