SUMO: regulating the regulator
Post-translational modifiers of the SUMO (Small Ubiquitin-related Modifier) family have emerged as key regulators of protein function and fate. While the past few years have seen an enormous increase in knowledge on SUMO enzymes, substrates, and consequences of modification,regulation of SUMO conjug...
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| Other Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2006
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| In: |
Cell division
Year: 2006, Volume: 1, Issue: 13, Pages: 1-8 |
| ISSN: | 1747-1028 |
| DOI: | 10.1186/1747-1028-1-13 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1186/1747-1028-1-13 Verlag, Volltext: http://webdoc.sub.gwdg.de/pub/med/2007/biomed/2006-melchior.pdf Resolving-System, Volltext: http://dx.doi.org/10.1186/1747-1028-1-13 
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| Author Notes: | Guillaume Bossis and Frauke Melchior |
| Summary: | Post-translational modifiers of the SUMO (Small Ubiquitin-related Modifier) family have emerged as key regulators of protein function and fate. While the past few years have seen an enormous increase in knowledge on SUMO enzymes, substrates, and consequences of modification,regulation of SUMO conjugation is far from being understood. This brief review will provide an overview on recent advances concerning (i) the interplay between sumoylation and other posttranslational modifications at the level of individual targets and (ii) global regulation of SUMO conjugation and deconjugation. |
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| Physical Description: | Online Resource |
| Format: | Systemvoraussetzungen: Acrobat reader. |
| ISSN: | 1747-1028 |
| DOI: | 10.1186/1747-1028-1-13 |