Structural Biology and Functional Genomics

Biomedical research will be revolutionised by the current efforts to sequence the human genome and the genomes of model organisms. Of the newly sequenced genes, 50% code for proteins of unknown functions, while as little as 5% of sequences in mammalian genomes code for proteins. New, genome-wide app...

Full description

Saved in:
Bibliographic Details
Corporate Authors: NATO Advanced Research Workshop on Structural Biology and Functional Genomics, (1998 :Trieste, Italy) (Author) , ebrary, Inc (Other)
Other Authors: Bradbury, Edwin Morton (Other) , Pongor, Sándor (Other)
Format: Book/Monograph
Language:English
Published: Dordrecht Springer Science+Business Media 1999
Series:NATO Science Series, Series 3. High Technology 71
Volumes / Articles: Show Volumes / Articles.
DOI:10.1007/978-94-011-4631-9
Online Access:Verlag, Volltext: http://site.ebrary.com/lib/alltitles/docDetail.action?docID=10668508
Resolving-System, Volltext: http://dx.doi.org/10.1007/978-94-011-4631-9
Get full text
Author Notes:edited by E. Morton Bradbury, Sándor Pongor
Description
Summary:Biomedical research will be revolutionised by the current efforts to sequence the human genome and the genomes of model organisms. Of the newly sequenced genes, 50% code for proteins of unknown functions, while as little as 5% of sequences in mammalian genomes code for proteins. New, genome-wide approaches are needed to draw together the knowledge that is emerging simultaneously in a number of fields of genome research. This volume is a high-level survey of the newly emerging concepts of structural biology and functional genomics for biologists, biochemists and medical researchers interested in genome research. Topics included are chromosome and chromatin organisation, novel DNA and RNA structures, DNA flexibility, supercoiling, prediction of protein functions, strategies for large scale structural analysis, and computer modelling
Physical Description:Online Resource
ISBN:9789401146319
DOI:10.1007/978-94-011-4631-9