Structural Biology and Functional Genomics

Biomedical research will be revolutionised by the current efforts to sequence the human genome and the genomes of model organisms. Of the newly sequenced genes, 50% code for proteins of unknown functions, while as little as 5% of sequences in mammalian genomes code for proteins. New, genome-wide app...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Körperschaften: NATO Advanced Research Workshop on Structural Biology and Functional Genomics, (1998 :Trieste, Italy) (VerfasserIn) , ebrary, Inc (BerichterstatterIn)
Weitere Verfasser: Bradbury, Edwin Morton (BerichterstatterIn) , Pongor, Sándor (BerichterstatterIn)
Dokumenttyp: Book/Monograph
Sprache:Englisch
Veröffentlicht: Dordrecht Springer Science+Business Media 1999
Schriftenreihe:NATO Science Series, Series 3. High Technology 71
Volumes / Articles: Show Volumes / Articles.
DOI:10.1007/978-94-011-4631-9
Online-Zugang:Verlag, Volltext: http://site.ebrary.com/lib/alltitles/docDetail.action?docID=10668508
Resolving-System, Volltext: http://dx.doi.org/10.1007/978-94-011-4631-9
Volltext
Verfasserangaben:edited by E. Morton Bradbury, Sándor Pongor
Beschreibung
Zusammenfassung:Biomedical research will be revolutionised by the current efforts to sequence the human genome and the genomes of model organisms. Of the newly sequenced genes, 50% code for proteins of unknown functions, while as little as 5% of sequences in mammalian genomes code for proteins. New, genome-wide approaches are needed to draw together the knowledge that is emerging simultaneously in a number of fields of genome research. This volume is a high-level survey of the newly emerging concepts of structural biology and functional genomics for biologists, biochemists and medical researchers interested in genome research. Topics included are chromosome and chromatin organisation, novel DNA and RNA structures, DNA flexibility, supercoiling, prediction of protein functions, strategies for large scale structural analysis, and computer modelling
Beschreibung:Online Resource
ISBN:9789401146319
DOI:10.1007/978-94-011-4631-9