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Neurological soft signs in the clinical course of schizophrenia: results of a meta-analysis

Neurological soft signs (NSS) comprise subtle deficits in sensory integration, motor coordination, and sequencing of complex motor acts, which are typically observed in the majority of schizophrenia patients, including chronic cases and neuroleptic-naïve first-episode patients. However, recent stud...

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Bibliographic Details
Main Authors: Bachmann, Silke (Author) , Degen, Christina (Author) , Geider, Franz Josef (Author) , Schröder, Johannes (Author)
Format: Article (Journal)
Language:English
Published: 23 December 2014
In: Frontiers in psychiatry
Year: 2014, Volume: 5
ISSN:1664-0640
DOI:10.3389/fpsyt.2014.00185
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.3389/fpsyt.2014.00185
Verlag, lizenzpflichtig, Volltext: https://www.frontiersin.org/articles/10.3389/fpsyt.2014.00185/full
Verlag, Volltext: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274793/pdf/fpsyt-05-00185.pdf
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Author Notes:Silke Bachmann, Christina Degen, Franz Josef Geider and Johannes Schröder
Description
Summary:Neurological soft signs (NSS) comprise subtle deficits in sensory integration, motor coordination, and sequencing of complex motor acts, which are typically observed in the majority of schizophrenia patients, including chronic cases and neuroleptic-naïve first-episode patients. However, recent studies clearly demonstrate that NSS are not a static feature of schizophrenia but vary in the clinical course of the disorder. This effect was investigated in a meta-analysis based on 17 longitudinal studies published between 1992 and 2012.
NSS, chronicity, course, outcome, schizophrenia
Item Description:Gesehen am 14.10.2020
Physical Description:Online Resource
ISSN:1664-0640
DOI:10.3389/fpsyt.2014.00185

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