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Management hereditärer kolorektaler Syndrome: Update 2025: molekulare Diagnostik und Präzisionsmedizin : Leitthema by Härtel, Nicolai (Author) , Kaufmann, Mario (Author) , Reißfelder, Christoph (Author) ,

• Verlag, lizenzpflichtig, Volltext

Emerge of colorectal cancer in Lynch syndrome despite colonoscopy surveillance: a challenge of hide and seek by Helderman, Noah (Author) , van Leerdam, Monique E. (Author) , Kloor, Matthias (Author) , Ahadova, Aysel (Author) , Nielsen, Maartje (Author) ,

• Verlag, lizenzpflichtig, Volltext
• Verlag, lizenzpflichtig, Volltext

Beyond germline genetic testing - heterozygous pathogenic variants in PMS2 in two children with Osteosarcoma and Ependymoma by Kuhlen, Michaela (Author) , Golas, Mariola Monika (Author) , Schaller, Tina (Author) , Stadler, Nicole (Author) , Maier, Felicitas (Author) , Witt, Olaf (Author) , Frühwald, Michael (Author) ,

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Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospec... by Dominguez-Valentin, Mev (Author) , Haupt, Saskia (Author) , Heuveline, Vincent (Author) , Knebel Doeberitz, Magnus von (Author) , Weitz, Jürgen (Author) ,

• Verlag, kostenfrei, Volltext
• Verlag, kostenfrei, Volltext

Liquid biopsy-based early tumor and minimal residual disease detection: new perspectives for cancer predisposition syndromes by Bohaumilitzky, Lena (Author) , Gebert, Johannes (Author) , Knebel Doeberitz, Magnus von (Author) , Kloor, Matthias (Author) , Ahadova, Aysel (Author) ,

• Verlag, lizenzpflichtig, Volltext
• Verlag, lizenzpflichtig, Volltext

The different immune profiles of normal colonic mucosa in cancer-free Lynch syndrome carriers and Lynch syndrome colorectal cancer patients by Bohaumilitzky, Lena (Author) , Kluck, Klaus (Author) , Hüneburg, Robert (Author) , Gallon, Richard (Author) , Nattermann, Jacob (Author) , Kirchner, Martina (Author) , Kristiansen, Glen (Author) , Hommerding, Oliver (Author) , Pfuderer, Pauline Luise (Author) , Wagner, Lelia (Author) , Echterdiek, Fabian Friedrich (Author) , Kösegi, Svenja (Author) , Müller, Nico (Author) , Fischer, Konstantin (Author) , Nelius, Nina (Author) , Hartog, Ben (Author) , Borthwick, Gillian (Author) , Busch, Elena (Author) , Haag, Georg Martin (Author) , Bläker, Hendrik (Author) , Möslein, Gabriela (Author) , Knebel Doeberitz, Magnus von (Author) , Seppälä, Toni T. (Author) , Ahtiainen, Maarit (Author) , Mecklin, Jukka-Pekka (Author) , Bishop, D Timothy (Author) , Burn, John (Author) , Stenzinger, Albrecht (Author) , Budczies, Jan (Author) , Kloor, Matthias (Author) , Ahadova, Aysel (Author) ,

• Resolving-System, lizenzpflichtig, Volltext
• Verlag, lizenzpflichtig, Volltext

Artificial intelligence for detection of microsatellite instability in colorectal cancer - a multicentric analysis of a pre-screening tool for clinical application by Echle, Amelie (Author) , Ghaffari Laleh, N. (Author) , Quirke, P. (Author) , Grabsch, H. I. (Author) , Muti, H. S. (Author) , Saldanha, O. L. (Author) , Brockmoeller, S. F. (Author) , van den Brandt, P. A. (Author) , Hutchins, G. G. A. (Author) , Richman, S. D. (Author) , Horisberger, K. (Author) , Galata, Christian (Author) , Ebert, Matthias (Author) , Eckardt, Maximilian (Author) , Boutros, Michael (Author) , Horst, D. (Author) , Reißfelder, Christoph (Author) , Alwers, E. (Author) , Brinker, T. J. (Author) , Langer, R. (Author) , Jenniskens, J. C. A. (Author) , Offermans, K. (Author) , Mueller, W. (Author) , Gray, R. (Author) , Gruber, S. B. (Author) , Greenson, J. K. (Author) , Rennert, G. (Author) , Bonner, J. D. (Author) , Schmolze, D. (Author) , Chang-Claude, Jenny (Author) , Brenner, Hermann (Author) , Trautwein, C. (Author) , Boor, P. (Author) , Jaeger, D. (Author) , Gaisa, Nadine (Author) , Hoffmeister, Michael (Author) , West, N. P. (Author) , Kather, Jakob Nikolas (Author) ,

• Verlag, lizenzpflichtig, Volltext
• Verlag, lizenzpflichtig, Volltext

A rare large duplication of MLH1 identified in Lynch syndrome by Kumar, Abhishek (Author) , Paramasivam, Nagarajan (Author) , Bandapalli, Obul Reddy (Author) , Schlesner, Matthias (Author) , Chen, Tianhui (Author) , Sijmons, Rolf (Author) , Dymerska, Dagmara (Author) , Golebiewska, Katarzyna (Author) , Kuswik, Magdalena (Author) , Lubinski, Jan (Author) , Hemminki, Kari (Author) , Försti, Asta (Author) ,

• Verlag, lizenzpflichtig, Volltext
• Verlag, lizenzpflichtig, Volltext

Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report by Seppälä, Toni T. (Author) , Dominguez-Valentin, Mev (Author) , Crosbie, Emma J. (Author) , Engel, Christoph (Author) , Aretz, Stefan (Author) , Macrae, Finlay (Author) , Winship, Ingrid (Author) , Capella, Gabriel (Author) , Thomas, Huw (Author) , Hovig, Eivind (Author) , Nielsen, Maartje (Author) , Sijmons, Rolf H. (Author) , Bertario, Lucio (Author) , Bonanni, Bernardo (Author) , Tibiletti, Maria G. (Author) , Cavestro, Giulia M. (Author) , Mints, Miriam (Author) , Gluck, Nathan (Author) , Katz, Lior (Author) , Heinimann, Karl (Author) , Vaccaro, Carlos A. (Author) , Green, Kate (Author) , Lalloo, Fiona (Author) , Hill, James (Author) , Schmiegel, Wolff (Author) , Vangala, Deepak (Author) , Perne, Claudia (Author) , Strauß, Hans-Georg (Author) , Tecklenburg, Johanna (Author) , Holinski-Feder, Elke (Author) , Steinke-Lange, Verena (Author) , Mecklin, Jukka-Pekka (Author) , Plazzer, John-Paul (Author) , Pineda, Marta (Author) , Navarro, Matilde (Author) , Vida, Joan B. (Author) , Kariv, Revital (Author) , Rosner, Guy (Author) , Piñero, Tamara A. (Author) , Pavicic, Walter (Author) , Kalfayan, Pablo (Author) , Ten Broeke, Sanne W. (Author) , Jenkins, Mark A. (Author) , Sunde, Lone (Author) , Bernstein, Inge (Author) , Burn, John (Author) , Greenblatt, Marc (Author) , de Vos tot Nederveen Cappel, Wouter H. (Author) , Della Valle, Adriana (Author) , Lopez-Koestner, Francisco (Author) , Alvarez, Karin (Author) , Büttner, Reinhard (Author) , Görgens, Heike (Author) , Morak, Monika (Author) , Holzapfel, Stefanie (Author) , Hüneburg, Robert (Author) , Knebel Doeberitz, Magnus von (Author) , Loeffler, Markus (Author) , Redler, Silke (Author) , Weitz, Jürgen (Author) , Pylvänäinen, Kirsi (Author) , Renkonen-Sinisalo, Laura (Author) , Lepistö, Anna (Author) , Hopper, John L. (Author) , Win, Aung K. (Author) , Lindor, Noralane M. (Author) , Gallinger, Steven (Author) , Le Marchand, Loïc (Author) , Newcomb, Polly A. (Author) , Figueiredo, Jane C. (Author) , Thibodeau, Stephen N. (Author) , Therkildsen, Christina (Author) , Wadt, Karin A. W. (Author) , Mourits, Marian J. E. (Author) , Ketabi, Zohreh (Author) , Denton, Oliver G. (Author) , Rødland, Einar A. (Author) , Vasen, Hans (Author) , Neffa, Florencia (Author) , Esperon, Patricia (Author) , Tjandra, Douglas (Author) , Möslein, Gabriela (Author) , Rokkones, Erik (Author) , Sampson, Julian R. (Author) , Evans, D. G. (Author) , Møller, Pål (Author) ,

• Verlag, lizenzpflichtig, Volltext
• Verlag, lizenzpflichtig, Volltext

No difference in penetrance between truncating and missense/aberrant splicing pathogenic variants in MLH1 and MSH2: a prospective Lynch Syndrome Database study by Dominguez-Valentin, Mev (Author) , Plazzer, John-Paul (Author) , Sampson, Julian R. (Author) , Engel, Christoph (Author) , Aretz, Stefan (Author) , Jenkins, Mark A. (Author) , Sunde, Lone (Author) , Bernstein, Inge (Author) , Capella, Gabriel (Author) , Balaguer, Francesc (Author) , Macrae, Finlay (Author) , Winship, Ingrid M. (Author) , Thomas, Huw (Author) , Evans, Dafydd Gareth (Author) , Burn, John (Author) , Greenblatt, Marc (Author) , de Vos tot Nederveen Cappel, Wouter H. (Author) , Sijmons, Rolf H. (Author) , Nielsen, Maartje (Author) , Bertario, Lucio (Author) , Bonanni, Bernardo (Author) , Tibiletti, Maria Grazia (Author) , Cavestro, Giulia Martina (Author) , Lindblom, Annika (Author) , Valle, Adriana Della (Author) , Lopez-Kostner, Francisco (Author) , Alvarez, Karin (Author) , Gluck, Nathan (Author) , Katz, Lior (Author) , Heinimann, Karl (Author) , Vaccaro, Carlos A. (Author) , Nakken, Sigve (Author) , Hovig, Eivind (Author) , Green, Kate (Author) , Lalloo, Fiona (Author) , Hill, James (Author) , Vasen, Hans F. A. (Author) , Perne, Claudia (Author) , Büttner, Reinhard (Author) , Görgens, Heike (Author) , Holinski-Feder, Elke (Author) , Morak, Monika (Author) , Holzapfel, Stefanie (Author) , Hüneburg, Robert (Author) , Knebel Doeberitz, Magnus von (Author) , Loeffler, Markus (Author) , Rahner, Nils (Author) , Weitz, Jürgen (Author) , Steinke-Lange, Verena (Author) , Schmiegel, Wolff (Author) , Vangala, Deepak (Author) , Crosbie, Emma J. (Author) , Pineda, Marta (Author) , Navarro, Matilde (Author) , Brunet, Joan (Author) , Moreira, Leticia (Author) , Sánchez, Ariadna (Author) , Serra-Burriel, Miquel (Author) , Mints, Miriam (Author) , Kariv, Revital (Author) , Rosner, Guy (Author) , Piñero, Tamara Alejandra (Author) , Pavicic, Walter Hernán (Author) , Kalfayan, Pablo (Author) , Broeke, Sanne W. ten (Author) , Mecklin, Jukka-Pekka (Author) , Pylvänäinen, Kirsi (Author) , Renkonen-Sinisalo, Laura (Author) , Lepistö, Anna (Author) , Peltomäki, Päivi (Author) , Hopper, John L. (Author) , Win, Aung Ko (Author) , Buchanan, Daniel D. (Author) , Lindor, Noralane M. (Author) , Gallinger, Steven (Author) , Marchand, Loïc Le (Author) , Newcomb, Polly A. (Author) , Figueiredo, Jane C. (Author) , Thibodeau, Stephen N. (Author) , Therkildsen, Christina (Author) , Hansen, Thomas V. O. (Author) , Lindberg, Lars (Author) , Rødland, Einar Andreas (Author) , Neffa, Florencia (Author) , Esperon, Patricia (Author) , Tjandra, Douglas (Author) , Möslein, Gabriela (Author) , Seppälä, Toni T. (Author) , Møller, Pål (Author) ,

• Verlag, lizenzpflichtig, Volltext
• Verlag, lizenzpflichtig, Volltext

Distinct mutational profile of lynch dyndrome colorectal cancers diagnosed under regular colonoscopy surveillance by Ahadova, Aysel (Author) , Pfuderer, Pauline Luise (Author) , Ahtiainen, Maarit (Author) , Ballhausen, Alexej (Author) , Bohaumilitzky, Lena (Author) , Kösegi, Svenja (Author) , Müller, Nico (Author) , Tang, Yee Lin (Author) , Kosmalla, Kosima (Author) , Witt, Johannes (Author) , Endris, Volker (Author) , Stenzinger, Albrecht (Author) , Knebel Doeberitz, Magnus von (Author) , Bläker, Hendrik (Author) , Renkonen-Sinisalo, Laura (Author) , Lepistö, Anna (Author) , Böhm, Jan (Author) , Mecklin, Jukka-Pekka (Author) , Seppälä, Toni T. (Author) , Kloor, Matthias (Author) ,

• Verlag, lizenzpflichtig, Volltext
• Verlag, lizenzpflichtig, Volltext

Identification and management of Lynch syndrome in the Middle East and North African countries: outcome of a survey in 12 countries by Sina, Mohammad (Author) , Ghorbanoghli, Zeinab (Author) , Abedrabbo, Amal (Author) , Al-Mulla, Fahd (Author) , Sghaier, Rihab Ben (Author) , Buisine, Marie-Pierre (Author) , Cortas, George (Author) , Goshayeshi, Ladan (Author) , Hadjisavvas, Andreas (Author) , Hammoudeh, Wail (Author) , Hamoudi, Waseem (Author) , Jabari, Carol (Author) , Loizidou, Maria A. (Author) , Majidzadeh-A, Keivan (Author) , Marafie, Makia J. (Author) , Muslumov, Gurbankhan (Author) , Rifai, Laila (Author) , Seir, Rania Abu (Author) , Talaat, Suzan M. (Author) , Tunca, Berrin (Author) , Ziada-Bouchaar, Hadia (Author) , Velthuizen, Mary E. (Author) , Sharara, Ala I. (Author) , Ahadova, Aysel (Author) , Georgiou, Demetra (Author) , Vasen, Hans F. A. (Author) ,

• Verlag, kostenfrei, Volltext
• Verlag, kostenfrei, Volltext

Value of upper gastrointestinal endoscopy for gastric cancer surveillance in patients with Lynch syndrome by Ladigan, Swetlana (Author) , Vangala, Deepak B. (Author) , Engel, Christoph (Author) , Bucksch, Karolin (Author) , Hueneburg, Robert (Author) , Perne, Claudia (Author) , Nattermann, Jacob (Author) , Steinke-Lange, Verena (Author) , Rahner, Nils (Author) , Schackert, Hans K. (Author) , Weitz, Jürgen (Author) , Kloor, Matthias (Author) , Kuhlkamp, Judith (Author) , Nguyen, Huu Phuc (Author) , Moeslein, Gabriela (Author) , Strassburg, Christian (Author) , Morak, Monika (Author) , Holinski-Feder, Elke (Author) , Buettner, Reinhard (Author) , Aretz, Stefan (Author) , Loeffler, Markus (Author) , Schmiegel, Wolff (Author) , Pox, Christian (Author) , Schulmann, Karsten (Author) ,

• Verlag, kostenfrei, Volltext
• Verlag, kostenfrei, Volltext

Update on the pathology, genetics and somatic landscape of sebaceous tumours by Ferreira, Ingrid (Author) , Wiedemeyer, Katharina (Author) , Demetter, Pieter (Author) , Adams, David J. (Author) , Arends, Mark J. (Author) , Brenn, Thomas (Author) ,

• Verlag, lizenzpflichtig, Volltext
• Verlag, lizenzpflichtig, Volltext

Implications of hereditary origin on the immune phenotype of mismatch repair-deficient cancers: systematic literature review by Bohaumilitzky, Lena (Author) , Knebel Doeberitz, Magnus von (Author) , Kloor, Matthias (Author) , Ahadova, Aysel (Author) ,

• Verlag, kostenfrei, Volltext
• Verlag, kostenfrei, Volltext

Clinical-grade detection of microsatellite instability in colorectal tumors by deep learning by Echle, Amelie (Author) , Grabsch, Heike Irmgard (Author) , Quirke, Philip (Author) , van den Brandt, Piet A. (Author) , West, Nicholas P. (Author) , Hutchins, Gordon G. A. (Author) , Heij, Lara R. (Author) , Tan, Xiuxiang (Author) , Richman, Susan D. (Author) , Krause, Jeremias (Author) , Alwers, Elizabeth (Author) , Jenniskens, Josien (Author) , Offermans, Kelly (Author) , Gray, Richard (Author) , Brenner, Hermann (Author) , Chang-Claude, Jenny (Author) , Trautwein, Christian (Author) , Pearson, Alexander T. (Author) , Boor, Peter (Author) , Luedde, Tom (Author) , Gaisa, Nadine Therese (Author) , Hoffmeister, Michael (Author) , Kather, Jakob Nikolas (Author) ,

• Verlag, lizenzpflichtig, Volltext
• Verlag, lizenzpflichtig, Volltext

Cancer risks in Lynch syndrome, Lynch-like syndrome, and familial colorectal cancer type X: a prospective cohort study by Bucksch, Karolin (Author) , Zachariae, Silke (Author) , Aretz, Stefan (Author) , Büttner, Reinhard (Author) , Holinski-Feder, Elke (Author) , Holzapfel, Stefanie (Author) , Hüneburg, Robert (Author) , Kloor, Matthias (Author) , Knebel Doeberitz, Magnus von (Author) , Morak, Monika (Author) , Möslein, Gabriela (Author) , Nattermann, Jacob (Author) , Perne, Claudia (Author) , Rahner, Nils (Author) , Schmiegel, Wolff (Author) , Schulmann, Karsten (Author) , Steinke-Lange, Verena (Author) , Strassburg, Christian P. (Author) , Vangala, Deepak B. (Author) , Weitz, Jürgen (Author) , Loeffler, Markus (Author) , Engel, Christoph (Author) ,

• Verlag, lizenzpflichtig, Volltext
• Verlag, lizenzpflichtig, Volltext

Three molecular pathways model colorectal carcinogenesis in Lynch syndrome by Ahadova, Aysel (Author) , Gebert, Johannes (Author) , Endris, Volker (Author) , Kirchner, Martina (Author) , Stenzinger, Albrecht (Author) , Knebel Doeberitz, Magnus von (Author) , Kloor, Matthias (Author) ,

• Verlag, Volltext
• Verlag, Volltext

Copy number variation analysis and targeted NGS in 77 families with suspected Lynch syndrome reveals novel potential causative genes by Kayser, Katrin (Author) , Knebel Doeberitz, Magnus von (Author) , Bork, Peer (Author) ,

• Verlag, Volltext
• Verlag

Low density of FOXP3-positive T cells in normal colonic mucosa is related to the presence of beta2-microglobulin mutations in Lynch syndrome-associated colorectal cancer by Echterdiek, Fabian Friedrich (Author) , Janikovits, Jonas (Author) , Staffa, Laura (Author) , Müller, Meike (Author) , Lahrmann, Bernd (Author) , Frühschütz, Monika (Author) , Hartog, Benjamin (Author) , Nelius, Nina (Author) , Benner, Axel (Author) , Tariverdian, Mirjam (Author) , Knebel Doeberitz, Magnus von (Author) , Grabe, Niels (Author) , Kloor, Matthias (Author) ,

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