Identification of the consistently altered metabolic targets in human hepatocellular carcinoma
Cancer cells rely on metabolic alterations to enhance proliferation and survival. Metabolic gene alterations that repeatedly occur in liver cancer are largely unknown. We aimed to identify metabolic genes that are consistently deregulated, and are of potential clinical significance in human hepatoce...
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| Main Authors: | , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
September 2017
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| In: |
Cellular and Molecular Gastroenterology and Hepatology
Year: 2017, Volume: 4, Issue: 2, Pages: 303-323.e1 |
| ISSN: | 2352-345X |
| DOI: | 10.1016/j.jcmgh.2017.05.004 |
| Online Access: | Resolving-System, Volltext: http://dx.doi.org/10.1016/j.jcmgh.2017.05.004 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S2352345X17300863 |
| Author Notes: | Zeribe Chike Nwosu, Dominik Andre Megger, Seddik Hammad, Barbara Sitek, Stephanie Roessler, Matthias Philip Ebert, Christoph Meyer, and Steven Dooley |
| Summary: | Cancer cells rely on metabolic alterations to enhance proliferation and survival. Metabolic gene alterations that repeatedly occur in liver cancer are largely unknown. We aimed to identify metabolic genes that are consistently deregulated, and are of potential clinical significance in human hepatocellular carcinoma (HCC). |
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| Item Description: | Gesehen am 26.10.2018 |
| Physical Description: | Online Resource |
| ISSN: | 2352-345X |
| DOI: | 10.1016/j.jcmgh.2017.05.004 |