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Identification of the consistently altered metabolic targets in human hepatocellular carcinoma

Cancer cells rely on metabolic alterations to enhance proliferation and survival. Metabolic gene alterations that repeatedly occur in liver cancer are largely unknown. We aimed to identify metabolic genes that are consistently deregulated, and are of potential clinical significance in human hepatoce...

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Hauptverfasser: Nwosu, Zeribe C. (VerfasserIn) , Hammad, Seddik (VerfasserIn) , Rössler, Stephanie (VerfasserIn) , Ebert, Matthias (VerfasserIn) , Meyer, Christoph (VerfasserIn) , Dooley, Steven (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: September 2017
In: Cellular and Molecular Gastroenterology and Hepatology
Year: 2017, Jahrgang: 4, Heft: 2, Pages: 303-323.e1
ISSN:2352-345X
DOI:10.1016/j.jcmgh.2017.05.004
Online-Zugang:Resolving-System, Volltext: http://dx.doi.org/10.1016/j.jcmgh.2017.05.004
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S2352345X17300863
Volltext
Verfasserangaben:Zeribe Chike Nwosu, Dominik Andre Megger, Seddik Hammad, Barbara Sitek, Stephanie Roessler, Matthias Philip Ebert, Christoph Meyer, and Steven Dooley
Beschreibung
Zusammenfassung:Cancer cells rely on metabolic alterations to enhance proliferation and survival. Metabolic gene alterations that repeatedly occur in liver cancer are largely unknown. We aimed to identify metabolic genes that are consistently deregulated, and are of potential clinical significance in human hepatocellular carcinoma (HCC).
Beschreibung:Gesehen am 26.10.2018
Beschreibung:Online Resource
ISSN:2352-345X
DOI:10.1016/j.jcmgh.2017.05.004

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