Challenges to curing primary brain tumours

Brain cancer encompasses a diverse range of complex malignancies, many of which are associated with a poor prognosis and require more effective treatments. In this Position Paper, an international panel of clinicians and laboratory-based scientists convened by Cancer Research UK identify and discuss...

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Main Authors:	Aldape, Kenneth (Author) , Brindle, Kevin M. (Author) , Chesler, Louis (Author) , Chopra, Raj (Author) , Gajjar, Amar (Author) , Gilbert, Mark R. (Author) , Gottardo, Nicholas (Author) , Gutmann, David H. (Author) , Hargrave, Darren (Author) , Holland, Eric C. (Author) , Jones, David T. W. (Author) , Joyce, Johanna A. (Author) , Kearns, Pamela (Author) , Kieran, Mark W. (Author) , Mellinghoff, Ingo Kai (Author) , Merchant, Melinda (Author) , Pfister, Stefan (Author) , Pollard, Steven M. (Author) , Ramaswamy, Vijay (Author) , Rich, Jeremy N. (Author) , Robinson, Giles W. (Author) , Rowitch, David H. (Author) , Sampson, John H. (Author) , Taylor, Michael D. (Author) , Workman, Paul (Author) , Gilbertson, Richard J. (Author)
Format:	Article (Journal)
Language:	English
Published:	07 February 2019
In:	Nature reviews. Clinical oncology Year: 2019, Volume: 16, Issue: 8, Pages: 509-520
ISSN:	1759-4782
DOI:	10.1038/s41571-019-0177-5
Online Access:	Verlag, Volltext: https://doi.org/10.1038/s41571-019-0177-5 Verlag, Volltext: https://www.nature.com/articles/s41571-019-0177-5
Author Notes:	Kenneth Aldape, Kevin M. Brindle, Louis Chesler, Rajesh Chopra, Amar Gajjar, Mark R. Gilbert, Nicholas Gottardo, David H. Gutmann, Darren Hargrave, Eric C. Holland, David T.W. Jones, Johanna A. Joyce, Pamela Kearns, Mark W. Kieran, Ingo K. Mellinghoff, Melinda Merchant, Stefan M. Pfister, Steven M. Pollard, Vijay Ramaswamy, Jeremy N. Rich, Giles W. Robinson, David H. Rowitch, John H. Sampson, Michael D. Taylor, Paul Workman and Richard J. Gilbertson