Search Results - Hargrave, Darren
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The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial by Kilburn, Lindsay B. (Author) , Khuong-Quang, Dong-Anh (Author) , Hansford, Jordan R. (Author) , Landi, Daniel (Author) , van der Lugt, Jasper (Author) , Leary, Sarah E. S. (Author) , Driever, Pablo Hernáiz (Author) , Bailey, Simon (Author) , Perreault, Sébastien (Author) , McCowage, Geoffrey (Author) , Waanders, Angela J. (Author) , Ziegler, David S. (Author) , Witt, Olaf (Author) , Baxter, Patricia A. (Author) , Kang, Hyoung Jin (Author) , Hassall, Timothy E. (Author) , Han, Jung Woo (Author) , Hargrave, Darren R. (Author) , Franson, Andrea T. (Author) , Yalon Oren, Michal (Author) , Toledano, Helen (Author) , Larouche, Valérie (Author) , Kline, Cassie (Author) , Abdelbaki, Mohamed S. (Author) , Jabado, Nada (Author) , Gottardo, Nicholas G. (Author) , Gerber, Nicolas U. (Author) , Whipple, Nicholas S. (Author) , Segal, Devorah (Author) , Chi, Susan N. (Author) , Oren, Liat (Author) , Tan, Enrica E. K. (Author) , Müller, Sabine (Author) , Cornelio, Izzy (Author) , McLeod, Lisa (Author) , Zhao, Xin (Author) , Walter, Ashley (Author) , Da Costa, Daniel (Author) , Manley, Peter (Author) , Blackman, Samuel C. (Author) , Packer, Roger J. (Author) , Nysom, Karsten (Author) ,
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LOGGIC/FIREFLY-2: a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RA... by Tilburg, Cornelis M. van (Author) , Kilburn, Lindsay B. (Author) , Perreault, Sébastien (Author) , Schmidt, Rene (Author) , Azizi, Amedeo A. (Author) , Cruz-Martínez, Ofelia (Author) , Zápotocký, Michal (Author) , Scheinemann, Katrin (Author) , Meeteren, Antoinette Y. N. Schouten-van (Author) , Sehested, Astrid (Author) , Opocher, Enrico (Author) , Driever, Pablo Hernáiz (Author) , Avula, Shivaram (Author) , Ziegler, David S. (Author) , Capper, David (Author) , Koch, Arend (Author) , Sahm, Felix (Author) , Qiu, Jiaheng (Author) , Tsao, Li-Pen (Author) , Blackman, Samuel C. (Author) , Manley, Peter (Author) , Milde, Till (Author) , Witt, Ruth (Author) , Jones, David T. W. (Author) , Hargrave, Darren (Author) , Witt, Olaf (Author) ,
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Resistance, rebound, and recurrence regrowth patterns in pediatric low-grade glioma treated by MAPK inhibition: a modified Delphi approach to build international consensus-based de... by O’Hare, Patricia (Author) , Cooney, Tabitha (Author) , de Blank, Peter (Author) , Gutmann, David H (Author) , Kieran, Mark (Author) , Milde, Till (Author) , Fangusaro, Jason (Author) , Fisher, Michael (Author) , Avula, Shivaram (Author) , Packer, Roger (Author) , Fukuoka, Kohei (Author) , Mankad, Kshitij (Author) , Müller, Sabine (Author) , Waanders, Angela J (Author) , Opocher, Enrico (Author) , Bouffet, Eric (Author) , Raabe, Eric (Author) , Werle, Natacha Entz (Author) , Azizi, Amedeo A (Author) , Robison, Nathan J (Author) , Hernáiz Driever, Pablo (Author) , Russo, Mark (Author) , Schouten, Netteke (Author) , Tilburg, Cornelis M. van (Author) , Sehested, Astrid (Author) , Grill, Jacques (Author) , Bandopadhayay, Pratiti (Author) , Kilday, John-Paul (Author) , Witt, Olaf (Author) , Ashley, David M (Author) , Ertl-Wagner, Birgit Betina (Author) , Tabori, Uri (Author) , Hargrave, Darren R. (Author) ,
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Consensus framework for conducting phase I/II clinical trials for children, adolescents, and young adults with pediatric low-grade glioma: guidelines established by the Internation... by Müller, Sabine (Author) , Fangusaro, Jason (Author) , Thomas, Arzu Onar (Author) , Jacques, Thomas S (Author) , Bandopadhayay, Pratiti (Author) , de Blank, Peter (Author) , Packer, Roger J (Author) , Fouladi, Maryam (Author) , van Meeteren, Antoinette Schouten (Author) , Jones, David T. W. (Author) , Perry, Arie (Author) , Nakano, Yoshiko (Author) , Hargrave, Darren (Author) , Riedl, David (Author) , Robison, Nathan J (Author) , Partanen, Marita (Author) , Fisher, Michael J (Author) , Witt, Olaf (Author) ,
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Comments and controversies in oncology: the tribulations of trials developing ONC201 by Hansford, Jordan R. (Author) , Bouche, Gauthier (Author) , Ramaswamy, Vijay (Author) , Jabado, Nada (Author) , Fonseca, Adriana (Author) , Moloney, Sam (Author) , Gottardo, Nicholas G. (Author) , Robinson, Giles W. (Author) , Gajjar, Amar (Author) , Tinkle, Christopher L. (Author) , Fisher, Paul G. (Author) , Foreman, Nicholas (Author) , Ashley, David M. (Author) , Ziegler, David S. (Author) , Eisenstat, David D. (Author) , Massimino, Maura (Author) , Witt, Olaf (Author) , Bartels, Ute (Author) , Rutkowski, Stefan (Author) , Hargrave, Darren (Author) , Fouladi, Maryam (Author) , Pfister, Stefan (Author) , Bouffet, Eric (Author) ,
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Precision medicine for childhood cancer: current limitations and future perspectives by McCabe, Martin G. (Author) , Geoerger, Birgit (Author) , Chesler, Louis (Author) , Hargrave, Darren (Author) , Parsons, D. Williams (Author) , Tilburg, Cornelis M. van (Author) , Schleiermacher, Gudrun (Author) , Hickman, John A. (Author) , George, Sally L. (Author) ,
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Dabrafenib plus Trametinib in pediatric glioma with BRAF V600 mutations by Bouffet, Eric (Author) , Hansford, Jordan R. (Author) , Garrè, Maria Luisa (Author) , Hara, Junichi (Author) , Plant-Fox, Ashley (Author) , Aerts, Isabelle (Author) , Locatelli, Franco (Author) , van der Lugt, Jasper (Author) , Papusha, Ludmila (Author) , Sahm, Felix (Author) , Tabori, Uri (Author) , Cohen, Kenneth J. (Author) , Packer, Roger J. (Author) , Witt, Olaf (Author) , Sandalic, Larissa (Author) , Bento Pereira da Silva, Ana (Author) , Russo, Mark (Author) , Hargrave, Darren R. (Author) ,
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Phase II trial of dabrafenib plus trametinib in relapsed/refractory BRAF V600-mutant pediatric high-grade glioma by Hargrave, Darren R. (Author) , Terashima, Keita (Author) , Hara, Junichi (Author) , Kordes, Uwe R. (Author) , Upadhyaya, Santhosh A. (Author) , Sahm, Felix (Author) , Bouffet, Eric (Author) , Packer, Roger J. (Author) , Witt, Olaf (Author) , Sandalic, Larissa (Author) , Kieloch, Agnieszka (Author) , Russo, Mark (Author) , Cohen, Kenneth J. (Author) ,
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Paediatric Strategy Forum for medicinal product development in mitogen-activated protein kinase pathway inhibitors: ACCELERATE in collaboration with the European Medicines Agency w... by Pearson, Andrew D. J. (Author) , Allen, Carl (Author) , Fangusaro, Jason (Author) , Hutter, Caroline (Author) , Witt, Olaf (Author) , Weiner, Susan (Author) , Reaman, Gregory (Author) , Russo, Mark (Author) , Bandopadhayay, Pratiti (Author) , Ahsan, Sama (Author) , Barone, Amy (Author) , Barry, Elly (Author) , de Rojas, Teresa (Author) , Fisher, Michael (Author) , Fox, Elizabeth (Author) , Bender, Julia Glade (Author) , Gore, Lia (Author) , Hargrave, Darren (Author) , Hawkins, Doug (Author) , Kreider, Brent (Author) , Langseth, Abraham J. (Author) , Lesa, Giovanni (Author) , Ligas, Franca (Author) , Marotti, Marcelo (Author) , Marshall, Lynley V. (Author) , Nasri, Kahina (Author) , Norga, Koen (Author) , Nysom, Karsten (Author) , Pappo, Alberto (Author) , Rossato, Gianluca (Author) , Scobie, Nicole (Author) , Smith, Malcolm (Author) , Stieglitz, Elliot (Author) , Weigel, Brenda (Author) , Weinstein, Amy (Author) , Viana, Ruth (Author) , Karres, Dominik (Author) , Vassal, Gilles (Author) ,
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A cell-based MAPK reporter assay reveals synergistic MAPK pathway activity suppression by MAPK inhibitor combination in BRAF-driven pediatric low-grade glioma cells by Usta, Diren (Author) , Sigaud, Romain (Author) , Buhl, Juliane (Author) , Selt, Florian (Author) , Marquardt, Viktoria (Author) , Pauck, David (Author) , Jansen, Jennifer (Author) , Pusch, Stefan (Author) , Ecker, Jonas (Author) , Hielscher, Thomas (Author) , Vollmer, Johanna (Author) , Sommerkamp, Alexander C. (Author) , Rubner, Tobias (Author) , Hargrave, Darren (Author) , Tilburg, Cornelis M. van (Author) , Pfister, Stefan (Author) , Jones, David T. W. (Author) , Remke, Marc (Author) , Brummer, Tilman (Author) , Witt, Olaf (Author) , Milde, Till (Author) ,
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Reply to ‘assembling the brain trust: the multidisciplinary imperative in neuro-oncology’ by Aldape, Kenneth (Author) , Brindle, Kevin M. (Author) , Chesler, Louis (Author) , Chopra, Raj (Author) , Gajjar, Amar (Author) , Gilbert, Mark R. (Author) , Gottardo, Nicholas (Author) , Gutmann, David H. (Author) , Hargrave, Darren (Author) , Holland, Eric C. (Author) , Jones, David T. W. (Author) , Joyce, Johanna A. (Author) , Kearns, Pamela (Author) , Kieran, Mark W. (Author) , Mellinghoff, Ingo Kai (Author) , Merchant, Melinda (Author) , Pfister, Stefan (Author) , Pollard, Steven M. (Author) , Ramaswamy, Vijay (Author) , Rich, Jeremy N. (Author) , Robinson, Giles W. (Author) , Rowitch, David H. (Author) , Sampson, John H. (Author) , Taylor, Michael D. (Author) , Workman, Paul (Author) , Gilbertson, Richard J. (Author) ,
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Challenges to curing primary brain tumours by Aldape, Kenneth (Author) , Brindle, Kevin M. (Author) , Chesler, Louis (Author) , Chopra, Raj (Author) , Gajjar, Amar (Author) , Gilbert, Mark R. (Author) , Gottardo, Nicholas (Author) , Gutmann, David H. (Author) , Hargrave, Darren (Author) , Holland, Eric C. (Author) , Jones, David T. W. (Author) , Joyce, Johanna A. (Author) , Kearns, Pamela (Author) , Kieran, Mark W. (Author) , Mellinghoff, Ingo Kai (Author) , Merchant, Melinda (Author) , Pfister, Stefan (Author) , Pollard, Steven M. (Author) , Ramaswamy, Vijay (Author) , Rich, Jeremy N. (Author) , Robinson, Giles W. (Author) , Rowitch, David H. (Author) , Sampson, John H. (Author) , Taylor, Michael D. (Author) , Workman, Paul (Author) , Gilbertson, Richard J. (Author) ,
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Molecular correlates of cerebellar mutism syndrome in medulloblastoma by Jabarkheel, Rashad (Author) , Amayiri, Nisreen (Author) , Yecies, Derek (Author) , Huang, Yuhao (Author) , Toescu, Sebastian (Author) , Nobre, Liana (Author) , Mabbott, Donald J. (Author) , Sudhakar, Sniya V. (Author) , Malik, Prateek (Author) , Laughlin, Suzanne (Author) , Swaidan, Maisa (Author) , Al Hussaini, Maysa (Author) , Musharbash, Awni (Author) , Chacko, Geeta (Author) , Mathew, Leni G. (Author) , Fisher, Paul G. (Author) , Hargrave, Darren (Author) , Bartels, Ute (Author) , Tabori, Uri (Author) , Pfister, Stefan (Author) , Aquilina, Kristian (Author) , Taylor, Michael D. (Author) , Grant, Gerald A. (Author) , Bouffet, Eric (Author) , Mankad, Kshitij (Author) , Yeom, Kristen W. (Author) , Ramaswamy, Vijay (Author) ,
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Related Subjects
Drug development
BRAF
Cancer therapeutics
Chemotherapy
Child
First-line
MAPK
MAPK pathway inhibitors
Paediatric cancer
Paediatric oncology
Paediatric strategy forum
Pediatric low-grade glioma
Phase II trials
Randomized controlled trials
Targeted therapies
Tovorafenib
cerebellar affective disorder
cerebellar mutism
medulloblastoma
pLGG
posterior fossa syndrome
postoperative cerebellar mutism