Epistatic effect of TLR3 and cGAS-STING-IKKε-TBK1-IFN signaling variants on colorectal cancer risk

The TLR3/cGAS-STING-IFN signaling has recently been reported to be disturbed in colorectal cancer due to deregulated expression of the genes involved. Our study aimed to investigate the influence of potential regulatory variants in these genes on the risk of sporadic colorectal cancer (CRC) in a Cze...

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Main Authors:	Catalano, Calogerina (Author) , Filho, Miguel Inacio da Silva (Author) , Frank, Christoph (Author) , Lu, Shun (Author) , Jiraskova, Katerina (Author) , Vymetalkova, Veronika (Author) , Levy, Miroslav (Author) , Liska, Vaclav (Author) , Vycital, Ondrej (Author) , Naccarati, Alessio (Author) , Vodickova, Ludmila (Author) , Hemminki, Kari (Author) , Vodicka, Pavel (Author) , Weber, Alexander N. R. (Author) , Försti, Asta (Author)
Format:	Article (Journal)
Language:	English
Published:	2020
In:	Cancer medicine Year: 2019, Volume: 9, Issue: 4, Pages: 1473-1484
ISSN:	2045-7634
DOI:	10.1002/cam4.2804
Online Access:	Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1002/cam4.2804 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/cam4.2804
Author Notes:	Calogerina Catalano, Miguel Inacio da Silva Filho, Christoph Frank, Shun Lu, Katerina Jiraskova, Veronika Vymetalkova, Miroslav Levy, Vaclav Liska, Ondrej Vycital, Alessio Naccarati, Ludmila Vodickova, Kari Hemminki, Pavel Vodicka, Alexander N.R. Weber, Asta Försti