Inherited genetic susceptibility to monoclonal gammopathy of unknown significance

Monoclonal gammopathy of undetermined significance (MGUS) is present in ∼2% of individuals age >50 years. The increased risk of multiple myeloma (MM) in relatives of individuals with MGUS is consistent with MGUS being a marker of inherited genetic susceptibility to MM. Common single-nucleotide po...

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Main Authors:	Weinhold, Niels (Author) , Johnson, David C. (Author) , Rawstron, Andrew C. (Author) , Försti, Asta (Author) , Doughty, Chi (Author) , Vijayakrishnan, Jayaram (Author) , Broderick, Peter (Author) , Dahir, Nasrin B. (Author) , Begum, Dil B. (Author) , Hosking, Fay J. (Author) , Yong, Kwee (Author) , Walker, Brian A. (Author) , Hoffmann, Per (Author) , Mühleisen, Thomas W. (Author) , Langer, Christian (Author) , Dörner, Elisabeth (Author) , Jöckel, Karl-Heinz (Author) , Eisele, Lewin (Author) , Nöthen, Markus M. (Author) , Hose, Dirk (Author) , Davies, Faith E. (Author) , Goldschmidt, Hartmut (Author) , Morgan, Gareth J. (Author) , Hemminki, Kari (Author) , Houlston, Richard S. (Author)
Format:	Article (Journal)
Language:	English
Published:	January 21, 2014
In:	Blood Year: 2014, Volume: 123, Issue: 16, Pages: 2513-2517
ISSN:	1528-0020
DOI:	10.1182/blood-2013-10-532283
Online Access:	Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1182/blood-2013-10-532283 Verlag, lizenzpflichtig, Volltext: https://ashpublications.org/blood/article/123/16/2513/32617/Inherited-genetic-susceptibility-to-monoclonal
Author Notes:	Niels Weinhold, David C. Johnson, Andrew C. Rawstron, Asta Försti, Chi Doughty, Jayaram Vijayakrishnan, Peter Broderick, Nasrin B. Dahir, Dil B. Begum, Fay J. Hosking, Kwee Yong, Brian A. Walker, Per Hoffmann, Thomas W. Mühleisen, Christian Langer, Elisabeth Dörner, Karl-Heinz Jöckel, Lewin Eisele, Markus M. Nöthen, Dirk Hose, Faith E. Davies, Hartmut Goldschmidt, Gareth J. Morgan, Kari Hemminki, and Richard S. Houlston