Buchumschlag

Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases

The multifunctional molecule netrin-1 is upregulated in various malignancies and has recently been presented as a major general player in tumorigenesis leading to tumor progression and maintenance in various animal models. However, there is still a lack of clinico-epidemiological data related to net...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Harter, Patrick Nikolaus (VerfasserIn) , Zinke, Jenny (VerfasserIn) , Scholz, Alexander (VerfasserIn) , Tichy, Julia Frederike (VerfasserIn) , Zachskorn, Cornelia (VerfasserIn) , Kvasnicka, Hans M. (VerfasserIn) , Goeppert, Benjamin (VerfasserIn) , Delloye-Bourgeois, Céline (VerfasserIn) , Hattingen, Elke (VerfasserIn) , Senft, Christian (VerfasserIn) , Steinbach, Joachim Peter (VerfasserIn) , Plate, Karl (VerfasserIn) , Mehlen, Patrick (VerfasserIn) , Schulte, Dorothea (VerfasserIn) , Mittelbronn, Michel Guy André (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: March 19, 2014
In: PLOS ONE
Year: 2014, Jahrgang: 9, Heft: 3
ISSN:1932-6203
DOI:10.1371/journal.pone.0092311
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1371/journal.pone.0092311
Verlag, lizenzpflichtig, Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092311
Volltext
Verfasserangaben:Patrick N. Harter, Jenny Zinke, Alexander Scholz, Julia Tichy, Cornelia Zachskorn, Hans M. Kvasnicka, Benjamin Goeppert, Céline Delloye-Bourgeois, Elke Hattingen, Christian Senft, Joachim P. Steinbach, Karl H. Plate, Patrick Mehlen, Dorothea Schulte, Michel Mittelbronn
Beschreibung
Zusammenfassung:The multifunctional molecule netrin-1 is upregulated in various malignancies and has recently been presented as a major general player in tumorigenesis leading to tumor progression and maintenance in various animal models. However, there is still a lack of clinico-epidemiological data related to netrin-1 expression. Therefore, the aim of our study was to elucidate the association of netrin-1 expression and patient survival in brain metastases since those constitute one of the most limiting factors for patient prognosis.
Beschreibung:Gesehen am 25.09.2020
Beschreibung:Online Resource
ISSN:1932-6203
DOI:10.1371/journal.pone.0092311

Ähnliche Einträge