Testing NTRK testing: wet‐lab and in silico comparison of RNA‐based targeted sequencing assays

NTRK fusions involving three neurotrophic tyrosine receptor kinase genes NTRK1, NTRK2, and NTRK3 and a variety of fusion partners were identified as oncogenic drivers across many cancer types.

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Bibliographic Details
Main Authors:	Pfarr, Nicole (Author) , Kirchner, Martina (Author) , Leichsenring, Jonas (Author) , Glade, Julia (Author) , Endris, Volker (Author) , Kazdal, Daniel (Author) , Schirmacher, Peter (Author) , Stenzinger, Albrecht (Author)
Format:	Article (Journal)
Language:	English
Published:	2020
In:	Genes, chromosomes & cancer Year: 2019, Volume: 59, Issue: 3, Pages: 178-188
ISSN:	1098-2264
DOI:	10.1002/gcc.22819
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/gcc.22819 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/gcc.22819
Author Notes:	Nicole Pfarr, Martina Kirchner, Ulrich Lehmann, Jonas Leichsenring, Sabine Merkelbach‐Bruse, Julia Glade, Michael Hummel, Fabian Stögbauer, Annika Lehmann, Marcel Trautmann, Jörg Kumbrink, Andreas Jung, Wolfgang Dietmaier, Volker Endris, Daniel Kazdal, Matthias Evert, David Horst, Hans Kreipe, Thomas Kirchner, Eva Wardelmann, Ulrik Lassen, Reinhard Büttner, Wilko Weichert, Manfred Dietel, Peter Schirmacher, Albrecht Stenzinger

Description
Summary:	NTRK fusions involving three neurotrophic tyrosine receptor kinase genes NTRK1, NTRK2, and NTRK3 and a variety of fusion partners were identified as oncogenic drivers across many cancer types.
Item Description:	First published: 25 October 2019 Gesehen am 26.01.2021
Physical Description:	Online Resource
ISSN:	1098-2264
DOI:	10.1002/gcc.22819