Analysis of isoaspartate in peptides by electrospray tandem mass spectrometry
In view of the significance of Asn deamidation and Asp isomerization to isoAsp at certain sites for protein aging and turnover, it was desirable to challenge the extreme analytical power of electrospray tandem mass spectrometry (ESI‐MS/MS) for the possibility of a site‐specific detection of this pos...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
31 December 2008
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| In: |
Protein science
Year: 2000, Jahrgang: 9, Heft: 11, Pages: 2260-2268 |
| ISSN: | 1469-896X |
| DOI: | 10.1110/ps.9.11.2260 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1110/ps.9.11.2260 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/10.1110/ps.9.11.2260 |
| Verfasserangaben: | Wolf D. Lehmann, Andreas Schlosser, Gerhard Erben, Rüdiger Pipkorn, Dirk Bossemeyer, and Volker Kinzel |
| Zusammenfassung: | In view of the significance of Asn deamidation and Asp isomerization to isoAsp at certain sites for protein aging and turnover, it was desirable to challenge the extreme analytical power of electrospray tandem mass spectrometry (ESI‐MS/MS) for the possibility of a site‐specific detection of this posttranslational modification. |
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| Beschreibung: | First published online: 31 December 2008 Elektronische Reproduktion der Druck-Ausgabe Gesehen am 23.02.2021 |
| Beschreibung: | Online Resource |
| ISSN: | 1469-896X |
| DOI: | 10.1110/ps.9.11.2260 |