Integrated molecular-morphologic meningioma classification: a multicenter retrospective analysis, retrospectively and prospectively validated

Meningiomas are the most frequent primary intracranial tumors. Patient outcome varies widely from benign to highly aggressive, ultimately fatal courses. Reliable identification of risk of progression for individual patients is of pivotal importance. However, only biomarkers for highly aggressive tum...

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Main Authors:	Maas, Sybren L. N. (Author) , Stichel, Damian (Author) , Hielscher, Thomas (Author) , Sievers, Philipp (Author) , Bergmeister-Berghoff, Anna Sophie (Author) , Schrimpf, Daniel (Author) , Sill, Martin (Author) , Euskirchen, Philipp (Author) , Blume, Christina (Author) , Patel, Areeba (Author) , Kardo, Helin (Author) , Reuss, David (Author) , Dohmen, Hildegard (Author) , Stein, Marco (Author) , Reinhardt, Annekathrin (Author) , Suwala, Abigail Kora (Author) , Wefers, Annika K. (Author) , Baumgarten, Peter (Author) , Ricklefs, Franz Lennard (Author) , Rushing, Elisabeth Jane (Author) , Bewerunge-Hudler, Melanie (Author) , Ketter, Ralf (Author) , Schittenhelm, Jens Florian (Author) , Jaunmuktane, Zane (Author) , Leu, Severina (Author) , Greenway, Fay E. A. (Author) , Bridges, Leslie R. (Author) , Jones, Timothy (Author) , Grady, Conor (Author) , Serrano, Jonathan (Author) , Golfinos, John (Author) , Sen, Chandra (Author) , Mawrin, Christian (Author) , Jungk, Christine (Author) , Hänggi, Daniel (Author) , Westphal, Manfred (Author) , Lamszus, Katrin (Author) , Etminan, Nima (Author) , Jungwirth, Gerhard (Author) , Herold-Mende, Christel (Author) , Unterberg, Andreas (Author) , Harter, Patrick Nikolaus (Author) , Wirsching, Hans-Georg (Author) , Neidert, Marian Christoph (Author) , Ratliff, Miriam (Author) , Platten, Michael (Author) , Snuderl, Matija (Author) , Aldape, Kenneth (Author) , Brandner, Sebastian (Author) , Hench, Jürgen Christian Hans (Author) , Frank, Stephan (Author) , Pfister, Stefan (Author) , Jones, David T. W. (Author) , Reifenberger, Guido (Author) , Acker, Till (Author) , Wick, Wolfgang (Author) , Weller, Michael (Author) , Preusser, Matthias (Author) , Deimling, Andreas von (Author) , Sahm, Felix (Author)
Format:	Article (Journal)
Language:	English
Published:	October 7, 2021
In:	Journal of clinical oncology Year: 2021, Volume: 39, Issue: 34, Pages: 3839-3852
ISSN:	1527-7755
DOI:	10.1200/JCO.21.00784
Online Access:	Resolving-System, kostenfrei: https://doi.org/10.1200/JCO.21.00784 Verlag, lizenzpflichtig, Volltext: https://ascopubs.org/doi/10.1200/JCO.21.00784
Author Notes:	Sybren L.N. Maas, Damian Stichel, Thomas Hielscher, Philipp Sievers, Anna S. Berghoff, Daniel Schrimpf, Martin Sill, Philipp Euskirchen, Christina Blume, Areeba Patel, Helin Dogan, David Reuss, Hildegard Dohmen, Marco Stein, Annekathrin Reinhardt, Abigail K. Suwala, Annika K. Wefers, Peter Baumgarten, Franz Ricklefs, Elisabeth J. Rushing, Melanie Bewerunge-Hudler, Ralf Ketter, Jens Schittenhelm, Zane Jaunmuktane, Severina Leu, Fay E.A. Greenway, Leslie R. Bridges, Timothy Jones, Conor Grady, Jonathan Serrano, John Golfinos, Chandra Sen, Christian Mawrin, Christine Jungk, Daniel Hänggi, Manfred Westphal, Katrin Lamszus, Nima Etminan, Gerhard Jungwirth, Christel Herold-Mende, Andreas Unterberg, Patrick N. Harter, Hans-Georg Wirsching, Marian C. Neidert, Miriam Ratliff, Michael Platten, Matija Snuderl, Kenneth D. Aldape, Sebastian Brandner, Jürgen Hench, Stephan Frank, Stefan M. Pfister, David T.W. Jones, Guido Reifenberger, Till Acker, Wolfgang Wick, Michael Weller, Matthias Preusser, Andreas von Deimling, and Felix Sahm