Organization of SNAREs within the Golgi Stack
Antero- and retrograde cargo transport through the Golgi requires a series of membrane fusion events. Fusion occurs at the cis- and trans-side and along the rims of the Golgi stack. Four functional SNARE complexes have been identified mediating lipid bilayer merger in the Golgi. Their function is ti...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
July 18, 2011
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| In: |
Cold Spring Harbor perspectives in biology
Year: 2011, Volume: 3, Issue: 10, Pages: 1-18 |
| ISSN: | 1943-0264 |
| DOI: | 10.1101/cshperspect.a005249 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1101/cshperspect.a005249 Verlag, lizenzpflichtig, Volltext: http://cshperspectives.cshlp.org/content/3/10/a005249 
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| Author Notes: | Jörg Malsam and Thomas H. Söllner |
| Summary: | Antero- and retrograde cargo transport through the Golgi requires a series of membrane fusion events. Fusion occurs at the cis- and trans-side and along the rims of the Golgi stack. Four functional SNARE complexes have been identified mediating lipid bilayer merger in the Golgi. Their function is tightly controlled by a series of reactions involving vesicle tethering and SM proteins. This network of protein interactions spatially and temporally determines the specificity of transport vesicle targeting and fusion within the Golgi. |
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| Item Description: | Gesehen am 09.08.2022 |
| Physical Description: | Online Resource |
| ISSN: | 1943-0264 |
| DOI: | 10.1101/cshperspect.a005249 |