Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry

Precision oncology requires diagnostic accuracy and robust detection of actionable alterations. The Pediatric Targeted Therapy (PTT) 2.0 program aims at improving diagnostic accuracy by addition of molecular analyses to the existing histological diagnosis and detection of actionable alterations for...

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Main Authors: Ecker, Jonas (Author) , Selt, Florian (Author) , Sturm, Dominik (Author) , Sill, Martin (Author) , Korshunov, Andrey (Author) , Hirsch, Steffen (Author) , Capper, David (Author) , Dikow, Nicola (Author) , Sutter, Christian (Author) , Müller, Carina (Author) , Sigaud, Romain (Author) , Eggert, Angelika (Author) , Simon, Thorsten (Author) , Niehues, Tim (Author) , Deimling, Andreas von (Author) , Pajtler, Kristian Wilfried (Author) , Tilburg, Cornelis M. van (Author) , Jones, David T. W. (Author) , Sahm, Felix (Author) , Pfister, Stefan (Author) , Witt, Olaf (Author) , Milde, Till (Author)
Format: Article (Journal)
Language:English
Published: February 2023
In: European journal of cancer
Year: 2023, Volume: 180, Pages: 71-84
ISSN:1879-0852
DOI:10.1016/j.ejca.2022.11.015
Online Access:lizenzpflichtig
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Author Notes:Jonas Ecker, Florian Selt, Dominik Sturm, Martin Sill, Andrey Korshunov, Steffen Hirsch, David Capper, Nicola Dikow, Christian Sutter, Carina Müller, Romain Sigaud, Angelika Eggert, Thorsten Simon, Tim Niehues, Andreas von Deimling, Kristian W. Pajtler, Cornelis M. van Tilburg, David T. W. Jones, Felix Sahm, Stefan M. Pfister, Olaf Witt, Till Milde
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Summary:Precision oncology requires diagnostic accuracy and robust detection of actionable alterations. The Pediatric Targeted Therapy (PTT) 2.0 program aims at improving diagnostic accuracy by addition of molecular analyses to the existing histological diagnosis and detection of actionable alterations for relapsed paediatric oncology patients, in cases with limited availability of tumour material.
Item Description:Online veröffentlicht am 25. November 2022, Artikelversion vom 19. Dezember 2022
Gesehen am 22.11.2023
Physical Description:Online Resource
ISSN:1879-0852
DOI:10.1016/j.ejca.2022.11.015