Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHSR), has two major functions: the stimulation of the growth hormone production and the stimulation of food intake. Accumulating evidence also indicates a role of ghrelin in cancer development.
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
28 September 2010
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| In: |
BMC gastroenterology
Year: 2010, Volume: 10, Issue: 1, Pages: 1-6 |
| ISSN: | 1471-230X |
| DOI: | 10.1186/1471-230X-10-112 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-230X-10-112 |
| Author Notes: | Daniele Campa, Barbara Pardini, Alessio Naccarati, Ludmila Vodickova, Jan Novotny, Verena Steinke, Nils Rahner, Elke Holinski-Feder, Monika Morak, Hans K. Schackert, Heike Görgens, Judith Kötting, Beate Betz, Matthias Kloor, Christoph Engel, Reinhard Büttner, Peter Propping, Asta Försti, Kari Hemminki, Roberto Barale, Pavel Vodicka, Federico Canzian |
| Summary: | Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHSR), has two major functions: the stimulation of the growth hormone production and the stimulation of food intake. Accumulating evidence also indicates a role of ghrelin in cancer development. |
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| Item Description: | Gesehen am 23.03.2023 |
| Physical Description: | Online Resource |
| ISSN: | 1471-230X |
| DOI: | 10.1186/1471-230X-10-112 |