Buchumschlag

Design of two ongoing clinical trials of tolvaptan in the treatment of pediatric patients with autosomal recessive polycystic kidney disease

Autosomal recessive polycystic kidney disease (ARPKD) is a hereditary condition characterized by massive kidney enlargement and developmental liver defects. Potential consequences during childhood include the need for kidney replacement therapy (KRT). We report the design of 2 ongoing clinical trial...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Mekahli, Djalila (Verfasst von) , Liebau, Max C. (Verfasst von) , Cadnapaphornchai, Melissa (Verfasst von) , Goldstein, Stuart L. (Verfasst von) , Greenbaum, Larry (Verfasst von) , Litwin, Mieczysław (Verfasst von) , Seeman, Tomas (Verfasst von) , Schaefer, Franz (Verfasst von) , Guay-Woodford, Lisa M. (Verfasst von)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 13 February 2023
In: BMC nephrology
Year: 2023, Jahrgang: 24, Pages: 1-11
ISSN:1471-2369
DOI:10.1186/s12882-023-03072-x
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12882-023-03072-x
Volltext
Verfasserangaben:Djalila Mekahli, Max C. Liebau, Melissa A. Cadnapaphornchai, Stuart L. Goldstein, Larry A. Greenbaum, Mieczyslaw Litwin, Tomas Seeman, Franz Schaefer and Lisa M. Guay-Woodford
Beschreibung
Zusammenfassung:Autosomal recessive polycystic kidney disease (ARPKD) is a hereditary condition characterized by massive kidney enlargement and developmental liver defects. Potential consequences during childhood include the need for kidney replacement therapy (KRT). We report the design of 2 ongoing clinical trials (Study 204, Study 307) to evaluate safety, tolerability, and efficacy of tolvaptan in children with ARPKD.
Beschreibung:Gesehen am 19.04.2023
Beschreibung:Online Resource
ISSN:1471-2369
DOI:10.1186/s12882-023-03072-x

Ähnliche Einträge